Treatment outcome of intrabony defects with guided tissue regeneration using space-providing suturing technique

Abstract

[한글]

이 연구의 목적은 특별히 고안된 suture technique을 기존 GTR membrane과함께 사용했을 때 space-provision이 얼마나 개선 되는지 알아보고, intrabony defect에 사용했을 때의 1년 후 임상 결과를 평가하는 것이다. 28명의 환자에서 clinical attachment level (CAL)과 probing depth (PD)가 각각 6mm이상인 34개의 interproximal intrabony defect를 골라 무작위로 두 치료 그룹 중 하나로 분류하였다. 실험군은 인접면 결손부를 치은박리 소파 한 뒤 expanded polytetrafluoroethylene (ePTFE) membranes을 space-providing suture technique으로 치아에 고정하였다. 대조군은 치은 박리 소파술만을 사용하여 치료하였다. 1년간의 관찰기간동안 환자들은 infection control program을 받았고 술 후 첫 6주 간은 매주, 그리고 다음 12개월은 세 달에 한 번씩 전문적인 치면 세마를 받았다.치료의 결과는 다음과 같다. 1) 실험군 대조군 모두에서 술 후 1년의 clinical attachment level (CAL)과 probing depth (PD)가 유의성 있게 개선되었다. 2) clinical attachment level (CAL)은 실험군이 대조군 보다 유의성 있게 더 큰 증가를 보였다. (실험군: 4.06mm±1.60mm, 대조군: 2.53mm±1.94mm, p<0.0174) 3) probing depth (PD)은 실험군이 대조군 보다 유의성 있게 더 큰 감소를 보였다. (실험군: 4.35± 1.46mm, 대조군: 2.53± 1.28mm, p<0.0005)결론적으로 expanded polytetrafluoroethylene (ePTFE) membranes을 space-providing suture technique으로 고정시키는 방법은 술 후 1년의 clinical attachment level (CAL)과 probing depth (PD)에서 치은 박리 소파술보다 임상적으로 더 우수한 결과를 보였다.

[영문]The purpose of this clinical trial was to demonstrate how the specially designed suturing technique enhanced space-provision by the conventional GTR membrane and evaluate the healing of intrabony defect with GTR procedures using this technique 1year after surgery.Thirty-four (34) defects in 25 patients were randomly assigned to 1 of 2 treatment groups. The test group was treated with expanded polytetrafluoroethylene (ePTFE) membranes and space-providing suturing technique; the second group was treated with an access flap procedure only. During the 1-year observation period, patients were subjected to a stringent infection control program including professional tooth cleaning every week for the first 6 weeks (two groups) and then checked every 3 months for 12 months (two groups).The results indicated that; 1) treatment modalities of the two groups resulted in clinically and statistically significant improvement in clinical attachment level (CAL) and probing depth (PD) at 1year; 2) a significantly greater amount of CAL gain (P<0.0174) was observed in the test group (4.06±1.60 mm) with respect to the control group (2.53±1.94mm); 3) a significantly greater amount of PD reduction (P<0.0005) was observed in the test group (4.35±1.46 mm) with respect to the control group (2.53±1.28mm)It can be concluded that the combination of space-providing suturing technique with expanded polytetrafluoroethylene (ePTFE) membranes resulted in significantly greater CAL and PD improvement than access flaps