Midterm observation of reverse reshaping in the heart after transcatheter closure of atrial septal defect and comparison between different age groups

Abstract

Background: Comparison between children and adult group about reverse reshaping of cardiac chambers after percutaneous ASD closure has rarely been reported. The aim of this study was to evaluate and compare the cardiovascular geometric changes after percutaneous ASD closure in children and adults.Methods and Results: Total of 166 ASD patients who underwent transcatheter occlusion with Amplatzer Septal occluder (AGA medical corporation, Plymouth, Minnesota, USA) from July, 2003 to July, 2005 were divided into 2 subgroups according to patients’ age as group I (less than 18 years of age) and group II (18 years of age or older), and their echocardiographic parameters were retrospectively analyzed. Right atrial diameter and right ventricle end diastolic diameter (RVEDD) showed statistically significant decrease (p<0.01) and left atrial diameter and left ventricular end diastolic diameter showed statistically significant increase (p<0.01) in both groups. The tricuspid regurgitation area index showed statistically significant decrease (p<0.01) and mitral regurgitation area index (MRAI) showed statistically significant increase (p=0.04). The change in RVEDD before and after the procedure was significantly higher in group II than in group I (p=0.048) and the change in MRAI was also significantly higher in group II than in group I (p=0.05).Conclusions: Therefore, patients who are considered for transcatheter closure of secundum ASD, MR should be carefully examined before and after the procedure.