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Multi-channel near-infrared spectroscopy imaging system for improvement of diagnostic accuracy in localized prostate cancer

Other Titles
 국소 전립선암의 위치결정 정확도 향상을 위한 다채널 근적외선분광 시스템 
Authors
 김승섭 
Department
 Dept. of Radiology (영상의학교실) 
Issue Date
2014
Description
Dept. of Medicine/석사
Abstract
Purpose: The purpose of this study was to develop a multi-channel NIRS (near-infrared spectroscopy) system for improvement of diagnostic accuracy in localized prostate cancer and to verify its diagnostic capability with the optical phantoms of prostate cancer.Materials and Methods: We developed the multi-channel NIRS system and the optical phantoms of normal prostate gland and localized prostate cancer. Computer software named Labview (National Instruments, Austin, TX, USA) was used to develop GUI (Graphic User Interface) which can process incoming signals and display them on the same monitor simultaneously. We measured NIRS signal attenuation through the developed phantoms and reconstructed 2D images based on the calculated absorption coefficients. We compared the reconstructed 2D images with the actual location of the localized prostate cancer component in the optical phantom.Results: Area with high absorption coefficients was well correlated with the actual location of the localized prostate cancer component in the optical phantom.Conclusion: We successfully demonstrated possibility of our NIRS system as a new potential imaging method for improvement of diagnostic accuracy in localized prostate cancer. In future, the NIRS system will possibly be combined with TRUS (trans-rectal ultrasonography), improving diagnostic accuracy of focal prostate cancer imaging and localization of target biopsy sites.
Files in This Item:
T013192.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 2. Thesis
Yonsei Authors
Kim, Seung-seob(김승섭) ORCID logo https://orcid.org/0000-0001-6071-306X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/134948
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