Study on the effect of ascorbic acid in miliaria and hypohidrosis
Authors
조계은
Issue Date
1971
Description
의학과/석사
Abstract
[한글]
Study on the Effect of Ascorbic Acid in Miliaria and Hypohydrosis
Kye Eun Cho
Department of Medical Science, Graduate School, Yonsei University
In an attempt to investigate the effective method for the prevention and
treatment of miliaria (prickly heat), ascorbic acid was administered orally to
experimentally produced miliaria and hypohidrosis, and good results were obtained.
There is general agreement that miliaria or prickly heat is associated with
occlusion of the outlets of the eccrine sweat gland but the precise nature of the
actual primary or initiating event is unknown. More over, the only effective
prevention and treatment of miliaria is maintaining the cool environment and the
topical or systemic medications has little common acceptance. Furthermore, these
very common pathological events play a major role in reducing military or
occupational effectiveness of soldiers and workmen who are employed under high
temperature and humidity. There is also no doubt that more effective measures for
the prevention and treatment of prickly heat and hypohidrosis are needed.
Recently, Hindson (1968) reported that ascorbic acid was effective in the
treatment of miliaria.
Miliaris and hypohidrosis were induced by occlusive dressing of one arm with
polyethylene vinyl film for 48 hours in thirty healthy men aged from 22 to 24 year
old.
The effect of prevention and treatment of ascorbic acid in maliaria and
hypohidrosis were observed respectively in two groups, one group which 1gm. of
ascorbic acid was administered daily for seven days and the other a placebo, before
and after inducing miliaria and hypohidrosis.
The following results were obtained.
1. All of the subjects developed miliaria and detectable hypohidrosis after
polyethylene occlusion for 48 hours.
2. Miliaria and hypohidrosis were in proportion but hypohidrosis was persisted
after the disappearance of miliaria.
3. Milaria and hypohidrosis, whatever its mechanism, were tend to be prevented
and treated with ascorbic acid.
From these findings, it is confirmed that ascorbic acid is effective in the
treatment of miliaria as the observation of Hindson.
In addition, ascorbic acid is suggested to be a useful drug for the prevention of
miliaria.
[영문]
In an attempt to investigate the effective method for the prevention and treatment of miliaria (prickly heat), ascorbic acid was administered orally to experimentally produced miliaria and hypohidrosis, and good results were obtained.
There is general agreement that miliaria or prickly heat is associated with occlusion of the outlets of the eccrine sweat gland but the precise nature of the actual primary or initiating event is unknown. More over, the only effective prevention and treatment of miliaria is maintaining the cool environment and the
topical or systemic medications has little common acceptance. Furthermore, these very common pathological events play a major role in reducing military or occupational effectiveness of soldiers and workmen who are employed under high temperature and humidity. There is also no doubt that more effective measures for
the prevention and treatment of prickly heat and hypohidrosis are needed.
Recently, Hindson (1968) reported that ascorbic acid was effective in the treatment of miliaria.
Miliaris and hypohidrosis were induced by occlusive dressing of one arm with polyethylene vinyl film for 48 hours in thirty healthy men aged from 22 to 24 year old.
The effect of prevention and treatment of ascorbic acid in maliaria and hypohidrosis were observed respectively in two groups, one group which 1gm. of ascorbic acid was administered daily for seven days and the other a placebo, before and after inducing miliaria and hypohidrosis.
The following results were obtained.
1. All of the subjects developed miliaria and detectable hypohidrosis after polyethylene occlusion for 48 hours.
2. Miliaria and hypohidrosis were in proportion but hypohidrosis was persisted after the disappearance of miliaria.
3. Milaria and hypohidrosis, whatever its mechanism, were tend to be prevented and treated with ascorbic acid.
From these findings, it is confirmed that ascorbic acid is effective in the treatment of miliaria as the observation of Hindson.
In addition, ascorbic acid is suggested to be a useful drug for the prevention of miliaria.