291 671

Cited 0 times in

Role of MR imaging for characterization of hepatic small interminate lesions on CT in patients with underlying extrahepatic carcinoma

Other Titles
 간외 원발암이 있는 환자군에서 전산화단층촬영상 불분명한 작은 간 병변의 감별진단에서 MRI의 역할 
 Dept. of Radiology (영상의학교실) 
Issue Date
Dept. of Medicine/석사

[영문]Objective: To retrospectively assess the value of adding gadolinium-enhanced dynamic imaging to standard ununenhanced magnetic resonance imaging (MRI) for characterising hypoattenuating hepatic lesions that are too small to characterise with multi-detector computed tomography (MDCT). Methods: Informed consent was waved, and Institutional Review Board approvals were obtained. Three hundred and forty-six small (≤2 cm) lesions (63 metastatic, 283 benign) in 183 patients with underlying carcinoma who underwent hepatic MRI after CT were retrospectively analysed. Two radiologists independently reviewed images and diagnoses were graded on an ordinal scale from 1 (definitely benign) to 5 (definitely malignant). Receiver operating characteristic analysis was used. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy, were also determined. Results: The areas under the curve of the unenhanced images alone and with dynamic images were 0.837 and 0.850 for reader 1 (p=0.616) and 0.771 and 0.783 for reader 2 (p=0.700). Descriptive statistical values demonstrated sensitivities of 76% and 80%, specificities of 93% and 95%, PPVs of 69% and 79%, NPVs of 95% and 95%, and accuracies of 90% and 92%, respectively. Conclusion: The value of adding three-phase contrast-enhanced MRI to unenhanced imaging did not reach statistical significance for characterising small hypoattenuating hepatic lesions on MDCT.
Files in This Item:
T011507.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 2. Thesis
Yonsei Authors
Baek, Song Ee(백송이) ORCID logo https://orcid.org/0000-0001-8146-2570
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.