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Changes in jugular bulb oxygen saturation during off-pump coronary artery bypass graft surgery

Authors
 J. Y. Kim  ;  Y. L. Kwak  ;  Y. W. Hong  ;  K. J. Yoo  ;  S. H. Kim  ;  Y. J. Oh 
Citation
 ACTA ANAESTHESIOLOGICA SCANDINAVICA, Vol.49(7) : 956-961, 2005 
Journal Title
ACTA ANAESTHESIOLOGICA SCANDINAVICA
ISSN
 0001-5172 
Issue Date
2005
MeSH
Adult ; Aged ; Carbon Dioxide/blood ; Cardiopulmonary Bypass ; Cerebrovascular Circulation* ; Coronary Artery Bypass* ; Humans ; Jugular Veins/metabolism* ; Middle Aged ; Oxygen/blood*
Keywords
Jugular bulb oxygen saturation ; off-pump coronary artery bypass ; brain ischemia
Abstract
Background:  The effect of haemodynamic derangement during coronary artery anastomosis in off-pump coronary artery bypass surgery on cerebral blood flow has not been elucidated. Jugular bulb oxygen saturation is a useful indicator of cerebral blood flow provided that the cerebral metabolic rate is constant. This study was designed to evaluate the changes in jugular bulb oxygen saturation during off-pump coronary artery bypass surgery.

Methods:  With IRB approval, 48 patients were included. After anaesthesia, an 18-G catheter was introduced into the jugular bulb. Haemodynamic variables and oxygen profiles from gas analysis of jugular bulb blood and arterial blood were obtained: after sternotomy (baseline); at 5 min after the beginning of the anastomosis of the left anterior descending artery, obtuse marginal artery, and right coronary artery; and after sternal closure.

Results:  Cardiac index and mixed venous oxygen saturation decreased significantly during anastomosis of all three arteries compared to the baseline value. Although the changes in jugular bulb oxygen saturation during anastomosis were statistically significant compared to its baseline value, jugular bulb oxygen saturation remained within normal limit throughout the study.

Conclusions:  Jugular bulb oxygen saturation, which represents the global cerebral oxygenation, was well maintained during the anastomosis of all coronary arteries despite significant haemodynamic changes during off-pump coronary artery bypass (OPCAB).
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2005.00739.x/abstract
DOI
10.1111/j.1399-6576.2005.00739.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Young Lan(곽영란) ORCID logo https://orcid.org/0000-0002-2984-9927
Kim, Seung Ho(김승호)
Oh, Young Jun(오영준) ORCID logo https://orcid.org/0000-0002-6258-5695
Yoo, Kyung Jong(유경종) ORCID logo https://orcid.org/0000-0002-9858-140X
Hong, Yong Woo(홍용우)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114751
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