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Endovascular Therapy Combined With Immunosuppressive Treatment for Pseudoaneurysms in Patients With Behçet's Disease

Authors
 Bon Kwon Koo  ;  Won-Heum Shim  ;  Byung-chul Chang  ;  Do-Yun Lee  ;  Yangsoo Jang  ;  Donghoon Choi  ;  Byoung Kwon Lee  ;  Young-sup Yoon 
Citation
 JOURNAL OF ENDOVASCULAR THERAPY, Vol.10(1) : 75-80, 2003 
Journal Title
 JOURNAL OF ENDOVASCULAR THERAPY 
ISSN
 1526-6028 
Issue Date
2003
MeSH
Adult ; Aneurysm, False/diagnosis ; Aneurysm, False/etiology ; Aneurysm, False/therapy* ; Behcet Syndrome/complications* ; Blood Vessel Prosthesis Implantation* ; Combined Modality Therapy ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Immunosuppressive Agents/therapeutic use* ; Male ; Middle Aged ; Stents* ; Tomography, X-Ray Computed ; Treatment Outcome
Keywords
12751935
Abstract
PURPOSE: To evaluate the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppression for the treatment of arterial pseudoaneurysms due to Behçet's disease. METHODS: Eleven pseudoaneurysms (3 in the abdominal aorta, 3 in the subclavian artery, and individual lesions in the brachiocephalic artery, renal artery, common iliac artery, common carotid artery, and the descending thoracic aorta) in 9 patients with Behçet's disease were treated with 10 stent-grafts and 1 self-expanding stent. All patients with elevated erythrocyte sedimentation rate (ESR) were treated with immunosuppressive agents (azathioprine, prednisolone) before and after the procedure. Results: Endovascular treatment was successful in all cases, without major adverse events. The ESR was reduced from 42.7+/-18.0 mm/h initially to 18.6+/-12.6 mm/h after immunosuppressive therapy prior to endovascular repair. During follow-up (mean 24.1+/-14.0 months, range 6-43), 8 of 11 lesions showed complete resolution. One stent-graft to treat a postsurgical recurrent carotid artery pseudoaneurysm was occluded, and an abdominal aortic pseudoaneurysm recurred; both patients stopped their medications. ESR during follow-up was 7.9+/-4.5 mm/h. CONCLUSIONS: Endovascular treatment for pseudoaneurysms due to Behçet's disease is feasible and effective when disease activity is strictly controlled with immunosuppressive therapy.
Full Text
http://jevtonline.org/doi/abs/10.1583/1545-1550(2003)010%3C0075:ETCWIT%3E2.0.CO;2
DOI
10.1583/1545-1550(2003)010<0075:ETCWIT>2.0.CO;2
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Do Yun(이도연)
Chang, Byung Chul(장병철)
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114119
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