176 302

Cited 32 times in

MR Evaluation of Radiation Synovectomy of the Knee by Means of Intra-articular Injection of Holmium-166-Chitosan Complex in Patients with Rheumatoid Arthritis : Results at 4-month Follow-up

Authors
 Sang Hoon Lee  ;  Jin-Suck Suh  ;  Soo Kon Lee  ;  Jungsik Song  ;  Jong Doo Lee  ;  Ho Seok Kim 
Citation
 KOREAN JOURNAL OF RADIOLOGY, Vol.4(3) : 170-178, 2003 
Journal Title
KOREAN JOURNAL OF RADIOLOGY
ISSN
 1229-6929 
Issue Date
2003
MeSH
Knee ; MR ; Rheumatoid arthritis ; Radiation synovectomy
Keywords
Knee ; MR ; Rheumatoid arthritis ; Radiation synovectomy
Abstract
Objective To determine whether MRI is able to demonstrate the effect of radiation synovectomy after the intra-articular injection of holmium-166-chitosan complex for the treatment of rheumatoid arthritis of the knee. Materials and Methods Fourteen patients aged 36-59 years were treated with 10-20 mCi of holmium-166-chitosan complex. A criterion for inclusion in this study was the absence of observable improvement after 3- or more months of treatment of the knee with disease-modifying anti-rheumatic drugs. MR images were acquired both prior to and 4-months after treatment. Clinical evaluation included the use of visual analog scales to assess pain, and the circumference of the knee and its range of motion were also determined. MR evaluation included measurement of the volume of synovial enhancement and wall thickness, the amount of joint effusion, and quantifiable scoring of bone erosion, bone edema and lymph nodes. Results Visual analog scale readings decreased significantly after radiation synovectomy (p <0.05). MRI showed that joint effusion decreased significantly (p <0.05), and that the volume of synovial enhancement tended to decrease, but to an insignificant extent (p = 0.107). Conclusion The decreased joint effusion noted at 4-month follow-up resulted from radiation synovectomy of the rheumatoid knee by means of intra-articular injection of holmium-166-chitosan complex.
Files in This Item:
T200302645.pdf Download
DOI
10.3348/kjr.2003.4.3.170
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Song, Jason Jungsik(송정식) ORCID logo https://orcid.org/0000-0003-0662-7704
Lee, Sang Hoon(이상훈)
Lee, Soo Kon(이수곤)
Lee, Jong Doo(이종두)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113322
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links