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The Surgical Effect of Callosotomy in the Treatment of Intractable Seizure

Authors
 Dong Seok Kim  ;  Kook Hee Yang  ;  Byung In Lee  ;  Joong Uhn Choi  ;  Jin Woo Chang  ;  Jong Hee Chang  ;  Tae Gon Kim 
Citation
 YONSEI MEDICAL JOURNAL, Vol.45(2) : 233-240, 2004 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2004
MeSH
Adolescent ; Adult ; Child ; Corpus Callosum/surgery* ; Electroencephalography ; Epilepsy, Generalized/pathology ; Epilepsy, Generalized/surgery* ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Prognosis ; TreatmentOutcome
Keywords
Intractable seizure ; callosotomy ; disconnection syndrome ; generalized seizure ; drop attack
Abstract
We evaluated the surgical effects of the callosotomy, particularly with respect to the effect of callosotomy in some seizure types and the extent of surgery. Twenty-one patients with a minimum follow-up of two year were enrolled. The most significant effect of callosotomy was the complete suppression of the generalized seizures associated with drop attack in 12 of 21 patients and seizure reduction of more than 75% in 6 of 21 patients. The surgical effect on the partial seizures was very variable. Transient disconnection syndrome appeared in 4 patients after anterior callosotomy. Total callosotomy by staged operation significantly suppressed generalized seizures associated with drop attack without any disconnection syndrome. Our data show that callosotomy is quite a good approach to the surgical treatment of drop attacks accompanied by disabling generalized seizures.
Files in This Item:
T200404497.pdf Download
DOI
10.3349/ymj.2004.45.2.233
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Seok(김동석)
Kim, Tae Gon(김태곤)
Yang, Kook Hee(양국희)
Lee, Byung In(이병인)
Chang, Jong Hee(장종희) ORCID logo https://orcid.org/0000-0003-1509-9800
Chang, Jin Woo(장진우) ORCID logo https://orcid.org/0000-0002-2717-0101
Choi, Joong Uhn(최중언)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112961
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