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피질원활추적운동계 간질성 활성화에 의한 간질성안진 : 전기생리학적 검사 및 신경방사선학적 소견

Other Titles
 Ictal Nystagmus by Epileptic Activation of Cortical Smooth Pursuit System: Electrophysiological and Neuroimaging Study 
Authors
 양재훈  ;  이동현  ;  이종복  ;  이종두  ;  박수철  ;  윤미진  ;  장지호  ;  송숙근 
Citation
 Journal of the Korean Neurological Association, Vol.22(5) : 465-471, 2004 
Journal Title
 Journal of the Korean Neurological Association 
ISSN
 1225-7044 
Issue Date
2004
Keywords
Epileptic nystagmus ; Electronystagmogram ; Smooth pursuit
Abstract
Background: Epileptic nystagmus is rare. There is no report in Korea about epileptic nystagmus by the activation of cortical smooth pursuit area. We studied a 29-year-male patient with nonconvulsive simple partial status epilepticus presenting as pure ictal nystagmus. Methods: The EEG including electrooculogram and electronystagmogram during ictus was done. Brain MRI including 99mTc-ECD SPECT and 18F-FDG PET were also done during ictus and repeated after complete relief from symptom. Subtraction images obtained from each of SPECT and PET were coregistrated onto MRI. Humphrey visual field test was done for documentation of visual field defect. Results: EEG was compatible with nonconvulsive status epilepticus arising from right mesial occipital area with 9-10 Hz frequency. Compensatory left beating nystagmus with midline crossing feature was noted and characteristic ipsiversive linear slow phase was presented in electronystagmogram. Brain neuroimages from MRI, 99mTc-ECD SPECT, and 18F-FDG PET revealed that the right parietotemporooccipital area was relevant area, but the right frontal eye field area was spared, which was much clear in SISCOM image. Conclusions: Clinical feature and electronystagmogram in this case showed typical epileptic nystagmus by activation of cortical smooth pursuit regions in which the relevant regions was posterior parietotemporooccipital area. The sparing of the frontal eye field area in this case suggested clearly that the epileptic nystagmus by the activation of cortical smooth pursuit regions could occur without involvement of frontal eye field area.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Park, Soo Chul(박수철)
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Lee, Jong Doo(이종두)
Lee, Jong Bok(이종복)
Chang, Jee Ho(장지호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112380
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