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자기 공명 영상을 이용한 허혈성 승모판 폐쇄 부전증의 원인기전 규명

Other Titles
 Etiologic Evaluation of Ischemic Mitral Regurgitation Using Cardiac MRI 
Authors
 최의영  ;  고영국  ;  최병욱  ;  유경종  ;  조승연  ;  정남식  ;  임세중  ;  심원흠  ;  장양수 
Citation
 KOREAN CIRCULATION JOURNAL, Vol.34(6) : 627-635, 2004 
Journal Title
 KOREAN CIRCULATION JOURNAL 
ISSN
 1738-5520 
Issue Date
2004
Keywords
Mitral regurgitation;Ischemic heart disease;Magnetic resonance imaging
Abstract
Background and Objectives:To evaluate the 3 dimensional geometric changes and the effect of revascularization in patients with ischemic mitral regurgitation (IMR), using cardiac magnetic resonance imaging (MRI). Subjects and Methods:Twenty-three patients with IMR, 10 with dilated cardiomyopathy with MR (DCM-MR) and 7 control subjects were enrolled. Hemodynamic indices, severity of MR, geometric parameters of mitral apparatus and myocardial viability were evaluated in all patients, and re-evaluated in the IMR patients 6 months after the revascularization. Results:The mitral tenting area (TAA) (334.1±111.7 mm2 vs. 222.9±123.0 mm2, p=0.16) and the sum of the tenting angles (TA) (72.9±12.9° vs. 51.5±11.1°, p<0.001) at the mid-systolic phase were increased in the IMR compared to the DCM-MR patients. In the IMR patients, the MR severity was positively correlated with the sum of the tethering lengths (r=0.522, p=0.011), LVESV (r=0.551, p=0.006), TAA (r=0.613, p=0.002) and TA (r=0.713, p<0.001). Of the 10 patients with viable myocardium, who had been revascularized without surgical repair of the mitral apparatus, the MR severity was decreased (28.3±10.4% vs. 16.5±7.6%, p=0.009) in 7 patients, with decreases in the sum of the tethering distances (51.2±13.9 mm vs. 40.2±9.1 mm, p=0.034), tenting area (299.2±93.8 mm2 vs. 215.0±63.6 mm2, p=0.036) and sum of the tenting angles (72.9±12.9° vs. 56.2±14.8°, p=0.015) 6 months after the revascularization. Conclusion:IMR was related with the geometric change in the mitral apparatus. Cardiac MRI can be an effective tool for evaluating these geometric changes and when formulating a treatment plan.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ko, Young Guk(고영국) ORCID logo https://orcid.org/0000-0001-7748-5788
Shim, Won Heum(심원흠)
Yoo, Kyung Jong(유경종) ORCID logo https://orcid.org/0000-0002-9858-140X
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Cho, Seung Yun(조승연)
Choi, Byoung Wook(최병욱) ORCID logo https://orcid.org/0000-0002-8873-5444
Choi, Eui Young(최의영) ORCID logo https://orcid.org/0000-0003-3732-0190
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/112225
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