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당뇨족에서 하지 동맥의 죽상 동맥 경화성 폐쇄와 경피적 중재술의 효과

Other Titles
 Atherosclerotic Obstruction of Lower Limb Arteries in Diabetic Foot: Effectiveness of Percutaneous Intervention 
Authors
 이상학  ;  최동훈  ;  조승연  ;  심원흠  ;  장양수  ;  이도연  ;  이진우  ;  차봉수  ;  고영국 
Citation
 KOREAN CIRCULATION JOURNAL, Vol.34(2) : 151-158, 2004 
Journal Title
 KOREAN CIRCULATION JOURNAL 
ISSN
 1738-5520 
Issue Date
2004
Keywords
Arteriosclerosis;Angioplasty;Diabetic foot ; 죽상 동맥 경화증;혈관 성형술;당뇨족
Abstract
Background and Objectives:Peripheral arterial disease is a risk factor for foot ulcers and amputation in diabetic patients. Percutaneous intervention of an obstructed lower limb artery is one of the treatments for diabetic foot;however, few data are available on this treatment and its effectiveness. The aim of this study was to investigate atherosclerotic obstruction in lower limb arteries and to evaluate the feasibility and effectiveness of percutaneous intervention in salvaging a lower limb with diabetic foot. Subjects and Methods:Fifty-two consecutive subjects (mean age:64) with diabetic foot underwent angiography of the lower limbs. In patients with significant narrowing (diameter stenosis >50%), percutaneous intervention was performed. Angiographic success was defined as restoration of distal blood flow with residual stenosis less than 30%. During follow-up, bypass surgery was performed when clinically indicated in some patients and the state of diabetic foot was evaluated. Results:Forty-nine patients (94%) showed atherosclerotic narrowings in lower limb arteries and 34 of them (65%) had significant lesions. Among those 34 subjects, interventions were carried out in 30 cases (balloon angioplasty in 11, stenting in 18, and intra-arterial thrombolytic therapy in 1). In the other 15, intervention was not indicated. Twenty-six (86%) of the 30 procedures were angiographically successful. During the follow-up (7±6 months), 12 subjects (57%) experienced wound healing with or without forefoot amputation or bypass surgery, whereas 3 had major amputation. Four patients died during the period. Conclusion:The majority of patients with diabetic foot had atherosclerotic obstruction in lower limb arteries. Percutaneous intervention may salvage limbs and reduce the rate of major amputation in patients with diabetic foot.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ko, Young Guk(고영국) ORCID logo https://orcid.org/0000-0001-7748-5788
Shim, Won Heum(심원흠)
Lee, Do Yun(이도연)
Lee, Sang Hak(이상학) ORCID logo https://orcid.org/0000-0002-4535-3745
Lee, Jin Woo(이진우) ORCID logo https://orcid.org/0000-0002-0293-9017
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Cho, Seung Yun(조승연)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/111911
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