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Curcuma xanthorrhiza oil이 함유된 구강분무액의 구취감소효과에 관한 임상적 연구

Other Titles
 Clinical anti-halitosis effects of oral spray containing Curcuma xanthorrhiza oil 
Authors
 김백일  ;  정승화  ;  김민영  ;  김해선  ;  유자혜  ;  권호근 
Citation
 Journal of Korean Academy of Oral Health (대한구강보건학회지), Vol.30(1) : 75-84, 2006 
Journal Title
Journal of Korean Academy of Oral Health(대한구강보건학회지)
ISSN
 1225-388x 
Issue Date
2006
Keywords
Curcuma xanthorrhiza oil ; halitosis ; oral spray ; xanthorrhizol
Abstract
Objectives: The purpose of this study was to determine effects of anti-halitosis for oral spray containing Curcuma xanthorrhiza oil(Cx) by in-vitro and in-vivo method.
Methods: This study used three kinds of oral sprays. First experimental group was containing 0.025% Curcuma xanthorrhiza oil plus 7% essential oil(CX+EO), second experimental group was containing 7% essential oil alone(EO), and control group was not containing any active ingredients. In-vitro trial, after mixing saliva from taking 10 subjects and adding these 20-200 ㎕ oral sprays, the levels of whole-mouth volatile sulphur compounds(VSCs) were measured by means of a gas chromatography(GC). In-vivo study, sixteen volunteers(7 male and 9 female), with a healthy oral status, were enrolled in a double-blind, cross-over design. After using above oral spray up to 3 hours, the levels of VSCs were measured by means of a GC and organoleptic analysis.
Results: The effects of anti-halitosis by GC using salivary samples from taking volunteers were that CX+EO group showed higher effects of anti-halitosis than control group in proportion to dosage(p<0.05). In the result of clinical trial of effects of anti-halitosis for sixteen volunteers, CX+EO group has more effectiveness of anti-halitosis than EO group in GC evaluation from 1 to 2 hours and in organoleptic analysis at 3 hours(p<0.05).
Conclusions: This study results that oral spray containing Curcuma xanthorrhiza oil showed more effectiveness of anti-halitosis than other control sprays.
Files in This Item:
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Preventive Dentistry and Public Oral Health (예방치과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ho Keun(권호근)
Kim, Baek Il(김백일) ORCID logo https://orcid.org/0000-0001-8234-2327
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/110414
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