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Optimal Delay Time for the Hepatic Parenchymal Enhancement at the Multidetector CT Examination

Authors
 Yong Eun Chung  ;  Ki Whang Kim  ;  Joo Hee Kim  ;  Joon Seok Lim  ;  Young Taik Oh  ;  Jae-Joon Chung  ;  Myeong-Jin Kim 
Citation
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.30(2) : 182-188, 2006 
Journal Title
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 
ISSN
 0363-8715 
Issue Date
2006
MeSH
Adolescent ; Adult ; Aged ; Analysis of Variance ; Child ; Contrast Media/pharmacokinetics* ; Female ; Humans ; Injections, Intravenous ; Iohexol/pharmacokinetics* ; Iopamidol/pharmacokinetics* ; Liver/blood supply* ; Liver/diagnostic imaging* ; Male ; Middle Aged ; Neoplasms/diagnostic imaging* ; Neoplasms/pathology ; Time Factors ; Tomography, Spiral Computed/methods*
Keywords
computed tomography (CT) ; contrast enhancement ; helical CT ; liver CT ; liver
Abstract
The objective of this study was to determine the optimal scan delay time after hepatic parenchymal enhancement using a 16-channel multidetector row helical CT (MDCT) scanner. Two hundred fifty-five consecutive patients underwent biphasic CT scans using a 16-channel MDCT. In group A (n = 125), two hepatic venous phase scans (HVP1 and HVP2) were obtained at 40 and 60 seconds, after 100-HU threshold time (T100HU) in the abdominal aorta. In group B (n = 130), HVP1 and HVP2 scans were obtained 50 and 70 seconds after T100HU. Both groups were divided into subgroups that were given different contrast media. Groups A1 and B1 received a contrast medium of 300 mgI/mL; groups A2 and B2 received a contrast medium of 370 mgI/mL. Each patient was injected with contrast medium at a dose of 2 mL/kg at a rate adjusted to the patient's body weight with a constant injection duration of 47 seconds. The attenuation values (HU) for the liver, portal vein, hepatic vein, and aorta were measured. The average HU was compared between the groups. Hepatic enhancement in the images obtained at 50 and 60 seconds after T100HU was greater (P < 0.05) than in images obtained at 40 and 70 seconds. These results were obtained with both contrast media. A few patients showed greater enhancement at a 40 seconds or 70 seconds. Hepatic enhancement was significantly greater in all scans using a contrast medium dose of 370 mgI/mL compared with the 300-mgI/mL dose (P < 0.05). Independent of the concentration of contrast medium, scan delays of 50 to 60 seconds after T100HU may provide optimal hepatic enhancement.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200603000-00003&LSLINK=80&D=ovft
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ki Whang(김기황)
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Kim, Joo Hee(김주희) ORCID logo https://orcid.org/0000-0001-5383-3602
Oh, Young Taik(오영택) ORCID logo https://orcid.org/0000-0002-4438-8890
Lim, Joon Seok(임준석) ORCID logo https://orcid.org/0000-0002-0334-5042
Chung, Yong Eun(정용은) ORCID logo https://orcid.org/0000-0003-0811-9578
Chung, Jae Joon(정재준) ORCID logo https://orcid.org/0000-0002-7447-1193
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108906
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