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Mechanical thrombectomy of acute iliofemoral deep vein thrombosis with use of an arrow-trerotola percutaneous thrombectomy device

Authors
 Kwang-Hun Lee  ;  Heon Han  ;  Kyo Joon Lee  ;  Choon-Sik Yoon  ;  Seung Hyoung Kim  ;  Jong Yoon Won  ;  Do Yun Lee 
Citation
 JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, Vol.17(3) : 487-495, 2006 
Journal Title
 JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY 
ISSN
 1051-0443 
Issue Date
2006
MeSH
Acute Disease ; Adult ; Aged ; Catheterization/instrumentation ; Feasibility Studies ; Female ; Femoral Vein ; Humans ; Iliac Vein ; Male ; Middle Aged ; Phlebography ; Thrombectomy/instrumentation* ; Thrombolytic Therapy ; Treatment Outcome ; Urokinase-Type Plasminogen Activator/administration & dosage ; Vascular Patency ; Venous Thrombosis/surgery*
Abstract
PURPOSE: To evaluate the immediate and 1-year clinical outcomes of mechanical thrombectomy with use of the Arrow-Trerotola percutaneous thrombectomy device (PTD) with or without low-dose urokinase in the treatment of acute iliofemoral deep vein thrombosis (DVT). MATERIALS AND METHODS: Mechanical thrombectomy with the PTD was performed in 25 patients with acute iliofemoral DVT. Thrombolytic therapy with low-dose urokinase was used in all patients without contraindications (n = 20). Other therapies used in combination included inferior vena cava filter insertion (n = 5), sheath aspiration thrombectomy (n = 25), and angioplasty and stent placement (n = 20). RESULTS: Initial technical and clinical success was achieved in all cases. In the 20 patients who had no contraindications to the use of urokinase, the dosage of urokinase did not exceed 1 million IU (range, 360,000-1,000,000 IU; mean, 640,000 IU). The mean time of urokinase infusion was 16 hours (range, 12-20). In five patients who had a contraindication to the use of urokinase, mechanical thrombectomy with the PTD was successful without the use of urokinase. There were no major complications. Primary patency of the stent-implanted common iliac vein segment was achieved at 1 year in 17 of 20 patients (85%). The overall 1-year clinical success rate was 92% (23 of 25 patients). Valvular insufficiency occurred in two patients (8%). CONCLUSION: The PTD is an effective mechanical thrombectomy device in the treatment of acute iliofemoral DVT with or without adjunctive urokinase thrombolysis.
Full Text
http://www.sciencedirect.com/science/article/pii/S1051044307610951
DOI
10.1097/01.RVI.0000202611.93784.76
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Won, Jong Yun(원종윤) ORCID logo https://orcid.org/0000-0002-8237-5628
Yoon, Choon Sik(윤춘식) ORCID logo https://orcid.org/0000-0003-2010-6710
Lee, Kwang Hun(이광훈)
Lee, Do Yun(이도연)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108852
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