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Stent-Graft Treatment of Infected Aortic and Arterial Aneurysms

 Kwang-Hun Lee  ;  Jong Yun Won  ;  Do Yun Lee  ;  Donghoon Choi  ;  Won-Heum Shim  ;  Byung Chul Chang  ;  Sang Joon Park 
 JOURNAL OF ENDOVASCULAR THERAPY, Vol.13(3) : 338-345, 2006 
Journal Title
Issue Date
Adult ; Aged ; Aged, 80 and over ; Aneurysm, Infected/drug therapy ; Aneurysm, Infected/mortality ; Aneurysm, Infected/surgery* ; Angioplasty* ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Aortic Aneurysm, Abdominal/drug therapy ; Aortic Aneurysm, Abdominal/mortality ; Aortic Aneurysm, Abdominal/surgery* ; Aortic Aneurysm, Thoracic/drug therapy ; Aortic Aneurysm, Thoracic/mortality ; Aortic Aneurysm, Thoracic/surgery* ; Blood Vessel Prosthesis Implantation* ; Feasibility Studies ; Female ; Follow-Up Studies ; Humans ; Iliac Aneurysm/drug therapy ; Iliac Aneurysm/mortality ; Iliac Aneurysm/surgery* ; Male ; Middle Aged ; Retrospective Studies ; Stents* ; Treatment Outcome
Purpose: To evaluate the feasibility and effectiveness of endovascular stent-graft repair of infected aortic and arterial aneurysms. Methods: Eight patients (5 men; mean age 56.6 years, range 30–85) with infected saccular aneurysms in the brachiocephalic artery (n=1), proximal descending thoracic aorta (n=1), infrarenal abdominal aorta (n=3), common iliac artery (n=1), and common femoral artery (n=2) were treated with stent-graft placement and intravenous antibiotic treatment for at least 6 weeks followed by case-specific administration of oral suppressive antibiotics. All patients were considered to be in the high-surgical-risk group. Results: Exclusion of the infected aneurysm was successful in all patients. However, 2 patients died within 30 days of uncontrolled sepsis, and 1 patient died at 6 months after rupture of a persistently infected aneurysm (37% mortality rate). Over a follow-up that ranged to 8 years, the 5 survivors showed complete resolution of the infected aneurysms; no stent-graft infection was observed during follow-up. Conclusion: The acceptable technical and clinical success of endovascular aneurysm repair makes this a promising treatment for infected aortic and arterial aneurysms. However, it is crucial that the infection is treated adequately prior to stent-graft placement.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Shim, Won Heum(심원흠)
Won, Jong Yun(원종윤) ORCID logo https://orcid.org/0000-0002-8237-5628
Lee, Kwang Hun(이광훈)
Lee, Do Yun(이도연)
Chang, Byung Chul(장병철)
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
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