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Magnetic resonance imaging of hepatocellular carcinoma using contrast media

Authors
 Myeong-Jin Kim  ;  Jin-Young Choi  ;  Yong Eun Chung  ;  Sun Young Choi 
Citation
 ONCOLOGY, Vol.75(suppl 1) : 72-82, 2008 
Journal Title
ONCOLOGY
ISSN
 0030-2414 
Issue Date
2008
MeSH
Aged ; Animals ; Carcinoma, Hepatocellular/diagnosis* ; Contrast Media* ; Dextrans ; Disease Models, Animal ; Ferrosoferric Oxide ; Humans ; Iron ; Liver Neoplasms/diagnosis* ; Magnetic Resonance Imaging/methods* ; Magnetite Nanoparticles ; Male ; Middle Aged ; Oxides ; Rats
Keywords
Hepatocellular carcinoma ; Magnetic resonance imaging ; Magnetic resonance contrast media
Abstract
Magnetic resonance imaging (MRI) has been widely used for evaluation of focal lesions associated with hepatic carcinogenesis including hepatocellular carcinoma (HCC). By providing better tissue contrast compared to ultrasonography and computed tomography, MRI is considered the most sensitive modality for diagnosis of HCC. Dynamic MRI using gadolinium-based extracellular fluid (ECF) agents is useful for detection of hypervascular tumors and lesion characterization but has limitations in the diagnosis of hypovascular HCCs and lesion characterization of nonhypervascular tumors. MRI using superparamagnetic iron oxide agents may be useful for detecting and characterizing lesions that were not seen on dynamic MRI using ECF agents, but finding well-differentiated HCC and differentiating it from a dysplastic nodule can be difficult in some cases. Hepatobiliary agents that can be used in both dynamic MRI and delayed hepatobiliary phase imaging have great potential for improving characterization of focal lesions associated with hepatic carcinogenesis. Further studies are necessary to determine their roles in evaluation and management of HCCs
Full Text
http://www.karger.com/Article/FullText/173427
DOI
10.1159/000173427
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Chung, Yong Eun(정용은) ORCID logo https://orcid.org/0000-0003-0811-9578
Choi, Sun Young(최선영)
Choi, Jin Young(최진영) ORCID logo https://orcid.org/0000-0002-9025-6274
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108431
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