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Radiological and Clinical Features of Sarcomatoid Hepatocellular Carcinoma in 11 Cases

Authors
 Hye Ryoung Koo  ;  Mi-Suk Park  ;  Myeong-Jin Kim  ;  Joon Suk Lim  ;  Jeong-Sik Yu  ;  Hur Jin  ;  Ki Whang Kim 
Citation
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.32(5) : 745-749, 2008 
Journal Title
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 
ISSN
 0363-8715 
Issue Date
2008
MeSH
Carcinoma, Hepatocellular/diagnostic imaging* ; Carcinoma, Hepatocellular/pathology* ; Female ; Humans ; Liver Neoplasms/diagnostic imaging* ; Liver Neoplasms/pathology* ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Retrospective Studies ; Tomography, X-Ray Computed
Keywords
Carcinoma, Hepatocellular/diagnostic imaging* ; Carcinoma, Hepatocellular/pathology* ; Female ; Humans ; Liver Neoplasms/diagnostic imaging* ; Liver Neoplasms/pathology* ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Retrospective Studies ; Tomography, X-Ray Computed
Abstract
OBJECTIVE: To evaluate the imaging and clinical findings of pathologically proven sarcomatoid hepatocellular carcinoma (HCC) in 11 cases. METHODS: We retrospectively reviewed the imaging findings and clinical features of 11 patients with pathologically proven sarcomatoid HCC at 2 university-based tertiary institutions from July 1997 to June 2006. RESULTS: The most common gross morphologies of sarcomatoid HCC were massive expanding pattern (n = 6 [54%]) or multinodular confluent (n = 5 [46%]) with partial encapsulation (n = 9 [82%]). The most common enhancement pattern was peripheral enhancement with central necrosis (n = 8 [72%]) without a dominant dynamic pattern of enhancement. Six (54%) of 11 patients were positive for hepatitis B surface antigen or hepatitis C virus antibody. Only 1 patient (9%) had more than 500 ng/mL of preoperative serum alpha-fetoprotein. CONCLUSIONS: In a patient with low-level alpha-fetoprotein and no history of viral hepatitis, sarcomatoid HCC usually presents as a large mass with peripheral enhancement, central necrosis, variable enhancement of the solid portion with or without tumor capsule, and intrahepatic metastasis.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200809000-00012&LSLINK=80&D=ovft
DOI
10.1097/RCT.0b013e3181591ccd
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ki Whang(김기황)
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Park, Mi-Suk(박미숙) ORCID logo https://orcid.org/0000-0001-5817-2444
Yu, Jeong Sik(유정식) ORCID logo https://orcid.org/0000-0002-8171-5838
Lim, Joon Seok(임준석) ORCID logo https://orcid.org/0000-0002-0334-5042
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/108223
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