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Fluorescent magnetic nanohybrids as multimodal imaging agents for human epithelial cancer detection

DC Field Value Language
dc.contributor.author허용민-
dc.contributor.author서진석-
dc.contributor.author양재문-
dc.contributor.author윤호근-
dc.date.accessioned2015-05-19T17:25:11Z-
dc.date.available2015-05-19T17:25:11Z-
dc.date.issued2008-
dc.identifier.issn0142-9612-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108112-
dc.description.abstractCetuximab conjugated fluorescent magnetic nanohybrids (CET-FMNHs) were synthesized for detection of human epithelial cancer via magnetic resonance (MR) and optical imaging. Spherical FMNHs consist of MnFe(2)O(4) magnetic nanocrystals encapsulated in pyrene-labeled PCL-b-PMAA as a surfactant prepared by a nano-emulsion method. FMNHs demonstrated excellent colloidal stability and biocompatibility for biomedical application. Antibody conjugated fluorescent magnetic nanohybrids (CET-FMNHs) served as effective agents for both magnetic resonance (MR) and fluorescence optical imaging of cancer cell lines.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2548~2555-
dc.relation.isPartOfBIOMATERIALS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAntibodies, Monoclonal*-
dc.subject.MESHAntibodies, Monoclonal, Humanized-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHCetuximab-
dc.subject.MESHEpithelial Cells/pathology*-
dc.subject.MESHErbB Receptors-
dc.subject.MESHFlow Cytometry-
dc.subject.MESHFluorescent Dyes*-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging-
dc.subject.MESHMicroscopy, Fluorescence-
dc.subject.MESHNanoparticles*-
dc.subject.MESHPolyesters/chemical synthesis-
dc.subject.MESHPolymethacrylic Acids/chemical synthesis-
dc.subject.MESHPyrenes/chemical synthesis-
dc.titleFluorescent magnetic nanohybrids as multimodal imaging agents for human epithelial cancer detection-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Biochemistry & Molecular Biology (생화학,분자생물학)-
dc.contributor.googleauthorJaemoon Yang-
dc.contributor.googleauthorEun-Kyung Lim-
dc.contributor.googleauthorHong Jae Lee-
dc.contributor.googleauthorJoseph Park-
dc.contributor.googleauthorSang Cheon Lee-
dc.contributor.googleauthorKwangyeol Lee-
dc.contributor.googleauthorHo-Geun Yoon-
dc.contributor.googleauthorJin-Suck Suh-
dc.contributor.googleauthorYong-Min Huh-
dc.contributor.googleauthorSeungjoo Haam-
dc.identifier.doi10.1016/j.biomaterials.2007.12.036-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04359-
dc.contributor.localIdA01916-
dc.contributor.localIdA02625-
dc.contributor.localIdA02315-
dc.relation.journalcodeJ00312-
dc.identifier.eissn1878-5905-
dc.identifier.pmid18329706-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0142961207010708-
dc.subject.keywordAntibodies, Monoclonal*-
dc.subject.keywordAntibodies, Monoclonal, Humanized-
dc.subject.keywordCell Line, Tumor-
dc.subject.keywordCetuximab-
dc.subject.keywordEpithelial Cells/pathology*-
dc.subject.keywordErbB Receptors-
dc.subject.keywordFlow Cytometry-
dc.subject.keywordFluorescent Dyes*-
dc.subject.keywordHumans-
dc.subject.keywordMagnetic Resonance Imaging-
dc.subject.keywordMicroscopy, Fluorescence-
dc.subject.keywordNanoparticles*-
dc.subject.keywordPolyesters/chemical synthesis-
dc.subject.keywordPolymethacrylic Acids/chemical synthesis-
dc.subject.keywordPyrenes/chemical synthesis-
dc.contributor.alternativeNameHuh, Yong Min-
dc.contributor.alternativeNameSuh, Jin Suck-
dc.contributor.alternativeNameYang, Jae Moon-
dc.contributor.alternativeNameYoon, Ho Geun-
dc.contributor.affiliatedAuthorHuh, Yong Min-
dc.contributor.affiliatedAuthorSuh, Jin Suck-
dc.contributor.affiliatedAuthorYoon, Ho Geun-
dc.contributor.affiliatedAuthorYang, Jae Moon-
dc.rights.accessRightsnot free-
dc.citation.volume29-
dc.citation.number16-
dc.citation.startPage2548-
dc.citation.endPage2555-
dc.identifier.bibliographicCitationBIOMATERIALS, Vol.29(16) : 2548-2555, 2008-
dc.identifier.rimsid35190-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
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