2 242

Cited 15 times in

A new method of screening for diabetic neuropathy using laser Doppler and photoplethysmography.

Authors
 Sung Woo Kim  ;  Soo Chan Kim  ;  Ki Chang Nam  ;  Eun Seok Kang  ;  Jae Jung Im  ;  Deok Won Kim 
Citation
 MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, Vol.46(1) : 61-67, 2008 
Journal Title
 MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 
ISSN
 0140-0118 
Issue Date
2008
MeSH
Aged ; Blood Volume ; Diabetic Neuropathies/diagnosis* ; Female ; Fingers/blood supply ; Humans ; Laser-Doppler Flowmetry/methods ; Male ; Mass Screening/methods ; Middle Aged ; Photoplethysmography/methods ; Sensitivity and Specificity ; Skin Temperature ; Toes/blood supply
Keywords
Diabetic neuropathy ; Photoplethysmography ; Laser Doppler ; Blood volume change ; Toe to finger ratio
Abstract
The purpose of this study is to suggest a simple, new method of screening for diabetic neuropathy. We measured blood volume changes by photoplethysmography (PPG) and blood perfusion by laser Doppler (LD) in the index fingers and big toes in 40 control subjects and in 50 (19 mild, 17 moderate, and 14 severe based on the nerve conduction velocity (NCV) test) and 35 diabetic patients with and without neuropathy, respectively. According to the results of PPG and LD measurements, the toe to finger ratios obtained from the neuropathic group were significantly higher than those from the control (p < 0.001) and the non-neuropathic groups (p < 0.001). Based on the NCV, the sensitivity of the LD method (92.0%) was higher than that of the PPG method (84.0%) for both left and right sides. Although specificity of the LD (92.8%) was also higher than the PPG (84.3%) bilaterally, the PPG showed better reproducibility (5.5 versus 9.5%) and a significant ratio increase with severity, while the LD did not. Our suggested PPG method using the toe to finger ratio is reliable, simple, economical, and accurate, and could become an effective new screening tool for the early detection of diabetic neuropathy.
Full Text
http://link.springer.com/article/10.1007%2Fs11517-007-0257-z
DOI
10.1007/s11517-007-0257-z
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eun Seok(강은석) ORCID logo https://orcid.org/0000-0002-0364-4675
Kim, Deok Won(김덕원)
Kim, Seong Woo(김성우)
Nam, Ki Chang(남기창)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107077
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse