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Quantitative Assessment of Lung Volumes using Multi-detector Row Computed Tomography (MDCT) in Patients with Chronic Obstructive Pulmonary Disease (COPD).

Other Titles
 만성 폐쇄성 폐질환 환자에서 MDCT를 사용한 폐용적의 정량분석 
 Sang Min Lee  ;  Jin Hur  ;  Tae Hoon Kim  ;  Sang Jin Kim  ;  Hyung Jung Kim 
 Journal of the Korean Society of Radiology, Vol.59(2) : 91-97, 2008 
Journal Title
 Journal of the Korean Society of Radiology 
Issue Date
Chronic obstructive pulmonary disease ; Computed tomography (CT) ; Lung volume measurements ; Chest
PURPOSE: To evaluate the clinical value of the multi-detector row computed tomography (MDCT) in the quantitative assessment of lung volumes and to assess the relationship between the MDCT results and disease severity as determined by a pulmonary function test (PFT) in Chronic Obstructive Pulmonary Disease (COPD) patients. MATERIALS AND METHODS: We performed a PFT and MDCT on 39 COPD patients. Using the GOLD classification, we divided the patients into three groups according to disease severity; stage I (mild, n=10), stage II (moderate, n=15), and stage III (severe, n=14). Using the pulmo-CT software program, we measured the proportion of lung volumes with attenuation values below -910 and -950 HU. RESULTS: The mean FEV1 (% of predicted) and FEV1/FVC was 82.2+/-2% and 66.2+/-3% in stage I, 53.5+/-11% and 52+/-6% in stage II, and 32.3+/-7% and 44.2+/-13% in stage III, respectively. Differences in lung volume percentages at each of the thresholds (-910 and -950 HU) among the 3 stages were statistically significant (p<0.01, p<0.01) and correlated well with the FEV1 and FEV1/FVC (r=-0.803, r=-0.766, r=-0.817, and r=-0.795, respectively). CONCLUSION: The volumetric measurement obtained by MDCT provides an accurate means of quantifying pulmonary emphysema
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Jin(김상진)
Kim, Tae Hoon(김태훈) ORCID logo https://orcid.org/0000-0003-3598-2529
Kim, Hyung Jung(김형중) ORCID logo https://orcid.org/0000-0003-2498-0683
Hur, Jin(허진) ORCID logo https://orcid.org/0000-0002-8651-6571
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