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Hepatic splenosis preoperatively diagnosed as hepatocellular carcinoma in a patient with chronic hepatitis B: A case report

Authors
 Gi-Hong Choi  ;  Man-Ki Ju  ;  June-Young Kim  ;  Chang-Moo Kang  ;  Kyung-Sik Kim  ;  Jin-Sub Choi  ;  Kwang-Hyub Han  ;  Mi-Suk Park  ;  Young-Nyun Park  ;  Woo-Jung Lee  ;  Byong-Ro Kim 
Citation
 Journal of Korean Medical Science, Vol.23(2) : 336-341, 2008 
Journal Title
 Journal of Korean Medical Science 
ISSN
 1011-8934 
Issue Date
2008
MeSH
Adult ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/diagnosis* ; Carcinoma, Hepatocellular/surgery ; Focal Nodular Hyperplasia/diagnosis ; Focal Nodular Hyperplasia/pathology ; Hepatitis B, Chronic/complications ; Hepatitis B, Chronic/diagnosis* ; Humans ; Liver/pathology* ; Liver Neoplasms/complications ; Liver Neoplasms/diagnosis* ; Liver Neoplasms/surgery ; Magnetic Resonance Imaging ; Male ; Splenosis/diagnosis* ; Tomography, X-Ray Computed ; Treatment Outcome ; alpha-Fetoproteins/biosynthesis
Keywords
Hepatic Splenosis ; Carcinoma ; Hepatocellular
Abstract
We report on a case of hepatic splenosis. A 32-yr-old man underwent a splenectomy due to trauma at the age of 6. He had been diagnosed as being a chronic hepatitis B-virus carrier 16 yr prior to the surgery. The dynamic computer tomography (CT) performed due to elevated serum alpha-fetoprotein (128 ng/mL) demonstrated two hepatic nodules, which were located near the liver capsule. A nodule in Segment IVa had a slight enhancement during both the arterial and portal phases, and another nodule in Segment VI showed a slight enhancement only in the portal phases. Dynamic magnetic resonance imaging (MRI) of the mass in Segment VI showed enhanced development in the arterial phases and slight hyperintensivity to the liver parenchyma in the portal phases. These imaging findings suggested a hypervascular tumor in the liver, which could be either focal nodular hyperplasia, adenoma, or hepatocellular carcinoma (HCC). Even though these lesions were diagnosed as HCC, some of the findings were not compatible with typical HCC. On dynamic CT and MRI, all lesions showed a slight arterial enhancement and did not show early venous washout. All lesions were located near the liver capsule. These findings, along with a history of splenectomy, suggested a diagnosis of hepatic splenosis.
Files in This Item:
T200800597.pdf Download
DOI
10.3346/jkms.2008.23.2.336
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Chang Moo(강창무) ORCID logo https://orcid.org/0000-0002-5382-4658
Kim, Kyung Sik(김경식) ORCID logo https://orcid.org/0000-0001-9498-284X
Kim, Byong Ro(김병로)
Kim, Jun Young(김준영)
Park, Mi-Suk(박미숙) ORCID logo https://orcid.org/0000-0001-5817-2444
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
Lee, Woo Jung(이우정) ORCID logo https://orcid.org/0000-0001-9273-261X
Joo, Man Ki(주만기) ORCID logo https://orcid.org/0000-0002-4112-7003
Choi, Gi Hong(최기홍) ORCID logo https://orcid.org/0000-0002-1593-3773
Choi, Jin Sub(최진섭)
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106831
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