158 201

Cited 0 times in

Sonographic features of the follicular variant of papillary thyroid carcinoma

Authors
 Jung Hyun Yoon  ;  Eun-Kyung Kim  ;  Soon Won Hong  ;  Jin Young Kwak  ;  Min Jung Kim 
Citation
 Journal of Ultrasound in Medicine, Vol.27(10) : 1431-1437, 2008 
Journal Title
 Journal of Ultrasound in Medicine 
ISSN
 0278-4297 
Issue Date
2008
Abstract
OBJECTIVE: The purpose of this study was to evaluate the sonographic findings of the follicular variant of papillary thyroid carcinoma (FVPTC) and to assess the role of preoperative fine-needle aspiration biopsy (FNAB). METHODS: The sonographic findings of 27 thyroid nodules in 26 patients (2 male and 24 female; mean age, 45 years) with surgically proven FVPTC were reviewed retrospectively. Findings were categorized according to the echogenicity, margin, shape, and presence of microcalcifications. Malignant findings included marked hypoechogenicity, irregular or microlobulated margins, a taller-than-wide shape, and microcalcifications. Thyroid nodules with a single malignant finding as described above were classified as malignant. All patients underwent sonographically guided FNAB, and the sensitivity of the cytologic results was calculated. RESULTS: Lesion sizes varied from 3 to 34 mm (mean, 15.2 mm), and lesions were most commonly solid (23 [85.2%]), hypoechoic (14 [51.9%]), and oval (17 [63%]) with well-defined margins (14 [51.9%]) and no microcalcifications (23 [85.2%]). Eighteen lesions (66.7%) were correctly classified as malignant, whereas 9 (33.3%) were classified as benign on the basis of sonographic criteria. Twenty-four samples were adequate for cytologic examination, and 3 were inadequate. Twenty-one of 24 diagnostic cytologic results (87.5%) were suspicious for papillary carcinoma (5 of 21 [20.8%]) or malignant (16 of 21 [66.7%]), whereas 3 lesions (12.5%) had benign results. The sensitivity of FNAB was 77.8% (21 of 27). CONCLUSIONS: The follicular variant of papillary thyroid carcinoma tends to have relatively benign sonographic features, such as hypoechogenicity, well-defined margins, an oval shape, and no microcalcifications, but most lesions were correctly classified as malignant by both sonography and FNAB. The possibility of FVPTC should be considered when thyroid nodules with a relatively benign sonographic appearance have suspicious or malignant FNAB results.
Files in This Item:
T200800566.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
곽진영(Kwak, Jin Young) ORCID logo https://orcid.org/0000-0002-6212-1495
김민정(Kim, Min Jung) ORCID logo https://orcid.org/0000-0003-4949-1237
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
홍순원(Hong, Soon Won) ORCID logo https://orcid.org/0000-0002-0324-2414
Export
RIS (EndNote)
XLS (Excel)
XML
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106779
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse