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신동맥 협착 환자에서 스텐트 삽입술 후 신기능의 변화

Other Titles
 Renal Outcome Following Stenting for Renal Artery Stenosis 
Authors
 장제현  ;  김현욱  ;  박선영  ;  김동기  ;  문성진  ;  최동훈  ;  심원흠  ;  김범석  ;  강신욱  ;  이호영  ;  한대석  ;  최규헌 
Citation
 Korean Journal of Nephrology, Vol.27(4) : 439-445, 2008 
Journal Title
Korean Journal of Nephrology
ISSN
 1975-9460 
Issue Date
2008
Keywords
Stenosis ; Stent ; Glomerular filtration rate ; Renal artery
Abstract
Purpose : Renal artery stenosis (RAS) causes or deteriorates hypertension and/or renal insufficiency, and is known as a progressive disease. The aim of this study is to reveal the change of renal function after stenting for RAS.
Methods : We retrospectively analyzed 66 patients between 1999 and 2005 who had stenting for RAS. Renal function was assessed by modified MDRD equation. According to baseline glomerular filtration rate (GFR), patients were divided into subgroups with group A (n=37, GFR ≥60 mL/min/1.73m2) or group B (n=29, GFR <60 mL/min/1.73m2). Clinical parameters were compared between two groups.
Results : A total of 66 patients (male:female=37:29) were studied. The mean age was 61±12 years old and the mean follow-up duration was 54±27 months. Sixty-one (92.4%) patients had hypertension, 20 (30.3%) had diabetes, and 48 (73%) had unilateral RAS. Group B was older than group A (65±9 vs. 58±14 years old). The mean body mass index of group B was higher than that of group A. In group A, there was a decrease in the MDRD GFR (from 75±11 to 70±15 mL/min/1.73m2; p=0.038). In contrast, in group B there was no significant change in the MDRD GFR (from 48±9 to 48±15 mL/min/1.73m2). In group A and group B, renal function has been improved in 3% and 24%, and stabilized in 70% and 52%, respectively.
Conclusion : Stenting for RAS has renal function preserving effect in patients with renal insufficiency. Therefore, stenting should be considered as a treatment modality in RAS patients even with deteriorated renal function.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Shin Wook(강신욱) ORCID logo https://orcid.org/0000-0002-5677-4756
Kim, Dong Ki(김동기)
Kim, Beom Seok(김범석) ORCID logo https://orcid.org/0000-0002-5732-2583
Kim, Hyun Wook(김현욱) ORCID logo https://orcid.org/0000-0002-4274-7562
Moon, Sung Jin(문성진)
Park, Sun Young(박선영)
Shim, Won Heum(심원흠)
Lee, Ho Yung(이호영)
Chang, Jae Hyun(장제현)
Choi, Kyu Hun(최규헌) ORCID logo https://orcid.org/0000-0003-0095-9011
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Han, Dae Suk(한대석)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106690
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