87 203

Cited 18 times in

Thrombus volume comparison between patients with and without hyperattenuated artery sign on CT

Authors
 E.Y. Kim  ;  E. Yoo  ;  H.Y. Choi  ;  J.W. Lee  ;  J.H. Heo 
Citation
 American Journal of Neuroradiology, Vol.29(2) : 359-362, 2008 
Journal Title
 American Journal of Neuroradiology 
ISSN
 0195-6108 
Issue Date
2008
MeSH
Cerebral Angiography/methods* ; Female ; Humans ; Infarction, Middle Cerebral Artery/diagnostic imaging* ; Male ; Middle Aged ; Middle Cerebral Artery/diagnostic imaging* ; Prognosis ; Reproducibility of Results ; Risk Assessment/methods ; Risk Factors ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods*
Keywords
Cerebral Angiography/methods* ; Female ; Humans ; Infarction, Middle Cerebral Artery/diagnostic imaging* ; Male ; Middle Aged ; Middle Cerebral Artery/diagnostic imaging* ; Prognosis ; Reproducibility of Results ; Risk Assessment/methods ; Risk Factors ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods*
Abstract
BACKGROUND AND PURPOSE: Although the hyperattenuated middle cerebral artery sign is known to be related to acute infarction, the volume of clot associated with it is not known. We investigated whether the presence or absence of hyperattenuated artery sign (HAS) on noncontrast CT (NCCT) can predict the thrombus volume. MATERIALS AND METHODS: We enrolled 90 consecutive patients with acute infarction who underwent both 5- and 1.25-mm NCCT and CT angiography (CTA). HAS was determined on 5-mm NCCT retrospectively. According to the location of thrombi, the patients were classified into ICA (ICA terminus/ICA and others), M1 (M1/both M1 and M2), and M2 (M2) groups. Thrombus volumes were measured by 1.25-mm NCCT and were compared between patients with and without HAS. RESULTS: Occlusion of major arteries was seen on CTA in 78 patients. HAS was found in 46 patients (59.0%). The mean thrombus volume was significantly larger in patients with HAS than in those without except for the M2 group (ICA group: [n = 14], 188.7 +/- 122.5 mm(3) versus 39.4 +/- 12.1 mm(3) [P = .022]; M1 group: [n = 42], 128.1 +/- 119.2 versus 56.8 +/- 32.5 [P = .005]; M2 group: [n = 22], 34.7 +/- 32.2 versus 20.0 +/- 20.0 [P = .18]). Thrombus volumes determined by receiver operating characteristic curve analysis were 52.36 mm(3) in the ICA group (sensitivity, 90.9%; specificity, 100%) and 53.96 mm(3) in the M1 group (sensitivity, 88.0%; specificity, 58.8%). CONCLUSION: Thrombus volumes were significantly larger in patients with HAS than in those without in ICA and M1 occlusions. The detection of HAS may provide an idea concerning rapid and dichotomized estimation of thrombus volume, which may be helpful for treatment decisions in potential candidates for thrombolysis.
Files in This Item:
T200800144.pdf Download
DOI
10.3174/ajnr.A0800
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Yeop(김응엽)
Yoo, Eun Hye(유은혜)
Lee, Jae Wook(이재욱)
Choi, Hye Yoen(최혜연)
Heo, Ji Hoe(허지회) ORCID logo https://orcid.org/0000-0001-9898-3321
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106276
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse