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Clinical Significance of MRI Findings During Medical Treatment for Tuberculous Spondylitis

Other Titles
 척추염 환자의 약물치료기간 중 추적 검사한 MRI소견 변화의 임상적 중요성 
Authors
 Dae Jung Kim  ;  Tae-Sub Chung  ;  Sang Hyun Suh  ;  Keun Su Kim  ;  Yong Eun Cho  ;  Youngsul Yoon  ;  Sam Soo Kim 
Citation
 Journal of the Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회지), Vol.13(2) : 146-151, 2009 
Journal Title
 Journal of the Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회지) 
ISSN
 1226-9751 
Issue Date
2009
Keywords
Tuberculoses ; Spinal ; Magnetic Resonance Imaging ; Spine ; Antibiotics ; Antitubercular
Abstract
Purpose : To evaluate magnetic resonance (MR) imaging features of non-surgically treated tuberculous spondylitis and to evaluate the relationships between these features and clinical outcomes. Materials and Methods : Data from ten patients (male:female=6:4, mean age=45 years) with clinically proven tuberculous spondylitis who were treated nonsurgically over three months were analyzed retrospectively from 2000 to 2007. MRI was performed at least three times for each patient, at baseline, every three or six months, and at the end of treatment. All images were analyzed by two radiologists. Results : The mean follow-up period for the MR examination was 10.1 months (range, 4-17 months). Six patients had clinically complete resolution of tuberculous spondylitis with medication treatment only. Four patients were treated with surgical management alongside medication. All ten patients were divided into two groups by clinical outcome; six patients with complete treatment and four patients with incomplete treatment. In the complete treatment group, follow-up MR findings showed a loss of subligamentous spread of abscesses, decreased size of abscesses, no interval changes in vertebral body heights, and fatty changes in spinal lesions. MR findings in the incomplete treatment group showed bone marrow edema extension to adjacent vertebra, extension of the abscesses, and decreased height of the vertebral bodies. Conclusion : During the nonsurgical management of tuberculous spondylitis, MR imaging may play a role in predicting patient response to antituberculous drug treatment.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Keun Su(김근수) ORCID logo https://orcid.org/0000-0002-3384-5638
Kim, Dae Jung(김대중)
Suh, Sang Hyun(서상현) ORCID logo https://orcid.org/0000-0002-7098-4901
Yoon, Young Sul(윤영설)
Chung, Tae Sub(정태섭)
Cho, Yong Eun(조용은) ORCID logo https://orcid.org/0000-0001-9815-2720
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105910
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