280 280

Cited 22 times in

The effects of Hydroxyapatite/Chitosan (H/C) Block scaffold in One-wall Intrabony Defect of Beagle Dogs

Authors
 Sung-Tae Kim  ;  Dong-Jin Kim  ;  Yoo-Jung Um  ;  Gyung-Joon Chae  ;  Chang-Sung Kim  ;  Yong-Keun Lee  ;  Seong-Ho Choi 
Citation
 Biomaterials Research (생체재료학회지), Vol.13(4) : 121-127, 2009 
Journal Title
 Biomaterials Research (생체재료학회지) 
ISSN
 1226-4601 
Issue Date
2009
Keywords
Bone substitutes ; Guided tissue regeneration ; Periodontal disease ; Tissue engineering ; Tissue scaffolds
Abstract
The effect of Hydroxyapatite/Chitosan (H/C) block scaffold and HA/β-TCP (H/T) particle on the regeneration was evaluated in one-wall intrabony defects in beagle dogs. Six male beagle dogs were used in this study. H/C block scaffold was manufactured by freeze-dried method. One-wall intrabony periodontal defects (4 × 4 mm) were surgically created. Prepared defects were randomly assigned and treated as follows. In surgical control group (C) the defects were not filled. In HA/β-TCP group (H/T), defects were filled with HA/β-TCP particle bone graft material. In HA/Chitosan block group (H/C), defects were filled with HA/Chitosan Block scaffold. In all groups, Mean values of regenerated bone, regenerated cementum, connective tissue, and epithelium were measured. H/C group showed less inflammatory reaction than other groups. It revealed good biocompatibility. This group also showed better cementum regeneration than any other group. However, due to the relatively rapid resorption of chitosan, space maintenance for regeneration seems to have been compromised. Bone regeneration was affected adversely with this rapid resorption. More favorable bone regeneration was found in H/T group because proper space was maintained with Β-TCP
Files in This Item:
T200905001.pdf Download
DOI
10.5051/jpis.2012.42.2.50
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Prosthodontics (보철과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Tae(김성태)
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Um, Yoo Jung(엄유정)
Lee, Yong Keun(이용근)
Chae, Gyung Joon(채경준)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105659
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse