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CT detection of subendocardial fat in myocardial infarction

 Sung Soo Ahn  ;  Young-Jin Kim  ;  Jin Hur  ;  Hye-Jeong Lee  ;  Tae Hoon Kim  ;  Kyu Ok Choe  ;  Byoung Wook Choi 
 AMERICAN JOURNAL OF ROENTGENOLOGY, Vol.192(2) : 532-537, 2009 
Journal Title
Issue Date
Adipose Tissue/diagnostic imaging* ; Contrast Media ; Coronary Angiography/methods* ; Female ; Humans ; Iopamidol ; Logistic Models ; Male ; Middle Aged ; Myocardial Infarction/pathology* ; Retrospective Studies ; Tomography, X-Ray Computed/methods*
cardiac imaging ; coronary arteries ; CT ; heart disease ; myocardial fat ; myocardial infarction
OBJECTIVE: We sought to systemically analyze the characteristics of fat accumulation in patients with myocardial infarction (MI) relative to various clinical parameters. MATERIALS AND METHODS: We included 161 patients (129 men, 32 women; mean age, 60.7 years) who had previously been diagnosed with MI and had undergone CT coronary angiography between February 2003 and April 2005. We analyzed the characteristics of myocardial fat, if present, and compared the clinical parameters of the patients with and those without myocardial fat. RESULTS: Myocardial fat was found in the subendocardial region in 36 (22.4%) patients with MI. In all cases, the myocardial fat was located in the subendocardial region and was typically detected in the left anterior descending artery territory (75%, n = 27). The mean attenuation value of myocardial fat was -29.6 HU on unenhanced CT. Myocardial fat was more frequently associated with a greater infarct age, milder coronary artery stenosis, and fewer number of diseased vessels. Patients with myocardial fat had more severe regional wall motion abnormalities on follow-up echocardiography. Age, sex, the presence of ST elevation or Q wave, elevated levels of cardiac enzymes, ejection fraction, and end-diastolic left ventricular dimension on follow-up echocardiography, as well as the presence of arrhythmia, were not significantly different between the two groups. CONCLUSION: Myocardial fat was detected in 22.4% of MI patients and was more frequently associated with a longer postinfarct period, milder coronary artery stenosis, fewer number of diseased vessels, and more severe regional wall motion abnormalities.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Young Jin(김영진) ORCID logo https://orcid.org/0000-0002-6235-6550
Kim, Tae Hoon(김태훈) ORCID logo https://orcid.org/0000-0003-3598-2529
Ahn, Sung Soo(안성수) ORCID logo https://orcid.org/0000-0002-0503-5558
Lee, Hye Jeong(이혜정) ORCID logo https://orcid.org/0000-0003-4349-9174
Choe, Kyu Ok(최규옥)
Choi, Byoung Wook(최병욱) ORCID logo https://orcid.org/0000-0002-8873-5444
Hur, Jin(허진) ORCID logo https://orcid.org/0000-0002-8651-6571
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