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신장이식 환자의 면역억제제 복용이행

Other Titles
 Medication Adherence in Patients Taking Immunosuppressants after Kidney Transplantation 
 정주희  ;  김영훈  ;  한덕종  ;  김광숙  ;  추상희 
 Journal of the Korean Society for Transplantation, Vol.24(4) : 289-297, 2010 
Journal Title
 Journal of the Korean Society for Transplantation  (대한이식학회지) 
Issue Date
BACKGROUND: Kidney transplant recipients inevitably take a life-long immunosuppressive medication to prevent graft rejection. Non-compliance to immunosuppressive medication is one of the main causes leading to acute and chronic rejection and diminished renal function, resulting in a return to dialysis, increased morbidity, or mortality with an additional health care cost and poor quality of life. The purpose of this study was to investigate actual medication compliance and its related factors. METHODS: A total of 222 functioning kidney transplant recipients were surveyed in a single center, and 25 patients were excluded due to incomplete responses. We reviewed medical records retrospectively, and the data were statistically analyzed with SPSS version 13.0. RESULTS: Among 197 patients, 113 (57.4%) were compliant to the immunosuppressive agents, and 84 (42.6%) recipients were non-compliant. Non-compliant patients were significantly younger (P=0.004), highly educated (P=0.004), employed (P=0.005), more likely to live alone (P=0.035), and drank more (P=0.001) than the compliant patients. Regarding psychosocial factors, more barriers (P=0.015), weak beliefs about the necessity of taking medications (P=0.001), strong beliefs about specific concerns related to medications (P=0.038), and low self efficacy (P=0.003) were identified in the non-compliant group compared with the compliant group. CONCLUSIONS: This study revealed that multiple factors affected medication compliance in patients taking immunosuppressants. It would be helpful to identify potential recipients with a risk for non-compliance based on their general characteristics and psychosocial factors, so they can be provided a specialized education program to promote compliance. This strategy may help produce more favorable long-term outcomes among kidney transplant recipients
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1. Journal Papers (연구논문) > 3. College of Nursing (간호대학) > Dept. of Nursing (간호학과)
1. Journal Papers (연구논문) > 3. College of Nursing (간호대학) > Dept. of Nursing (간호학과)
Yonsei Authors
김광숙(Kim, Gwang Suk) ORCID logo https://orcid.org/0000-0001-9823-6107
추상희(Chu, Sang Hui) ORCID logo https://orcid.org/0000-0001-6877-5599
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