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Anti-photoaging effects of 2-methoxy-5-(2-methyl propyl) pyrazine isolated from peach (Prunus persica (L.) Batsch)

Authors
 Sunghwa Han  ;  Kwang-Kyun Park  ;  Won-Yoon Chung  ;  Sang Kook Lee  ;  Jaekyung Kim  ;  Jae-Kwan Hwang 
Citation
 Food Science and Biotechnology, Vol.19(6) : 1667-1671, 2010 
Journal Title
 Food Science and Biotechnology 
ISSN
 1226-7708 
Issue Date
2010
Abstract
In this study, antioxidant and anti-photoaging activities of 2-methoxy-5-(2-methyl propyl) pyrazine (MMPP) isolated from peach (Prunus persica (L.) Batsch) were investigated in terms of matrix metalloproteinase (MMP)-1 and type-1 procollagen expression in ultraviolet (UV)-irradiated human skin fibroblasts. MMPP was obtained from the butanol fraction of a 95% ethanol extract of peach. The antioxidant and anti-photoaging activity of MMPP were assessed by 1,1-diphenyl-2-picrylhydrazy (DPPH), Western blot, and reverse trans-cription-polymerase chain reaction (RT-PCR) analyses. MMPP displayed radical scavenging activity, suppressed MMP-1 expression, and increased type-1 procollagen expression. These results support the use of MMPP from peach as an antiphotoaging compound.
Full Text
http://link.springer.com/article/10.1007%2Fs10068-010-0236-2#
DOI
10.1007/s10068-010-0236-2
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers
Yonsei Authors
박광균(Park, Kwang Kyun)
정원윤(Chung, Won Yoon) ORCID logo https://orcid.org/0000-0001-8428-9005
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102668
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