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Factors in the Breast Core Needle Biopsies of Atypical Ductal Hyperplasia that Can Predict Carcinoma in the Subsequent Surgical Excision Specimens

Authors
 Ja Seung Koo  ;  Min Jung Kim  ;  Eun-kyung Kim  ;  Woohee Jung 
Citation
 JOURNAL OF BREAST CANCER, Vol.13(2) : 132-137, 2010 
Journal Title
 JOURNAL OF BREAST CANCER 
ISSN
 1738-6756 
Issue Date
2010
Keywords
Breast hyperplasia ; Needle biopsy ; Risk factor
Abstract
PURPOSE: Our purpose was to identify the factors in a breast core needle biopsy (CNB) of atypical ductal hyperplasia (ADH) that are predictive for carcinoma in the subsequent excision specimens. METHODS: We performed a retrospective pathologic review of 50 cases that were diagnosed as ADH via the CNB and that had the corresponding excision specimens. RESULTS: The size of the largest ADH foci in the CNBs was 0.8+/-0.6 mm (mean+/-SD) for benign proliferative disease (BPD, n=12), 1.0+/-0.5 mm (mean+/-SD) for ADH (n=9) and 1.3+/-0.8 mm (mean+/-SD) for malignant lesions (n=29) in excision specimens (p=0.105). Among the 30 cases showing stromal alterations around the ducts with ADH in the CNBs, 9 cases (30.0%) were BPD or ADH and 21 cases (70.0%) were malignant lesions in the excision specimens (p=0.004). CONCLUSION: As the stromal alterations around the ADH were noted in the CNB, there was an increased likelihood that more advanced lesions would be identified in the surgical excision specimens
Files in This Item:
T201004103.pdf Download
DOI
10.4048/jbc.2010.13.2.132
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Koo, Ja Seung(구자승) ORCID logo https://orcid.org/0000-0003-4546-4709
Kim, Min Jung(김민정) ORCID logo https://orcid.org/0000-0003-4949-1237
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Jung, Woo Hee(정우희)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102610
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