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Renal stone associated with the ketogenic diet in a 5-year old girl with intractable epilepsy

Authors
 Ji Na Choi  ;  Ji Eun Song  ;  Jae Il Shin  ;  Heung Dong Kim  ;  Myung Joon Kim  ;  Jae Seung Lee 
Citation
 YONSEI MEDICAL JOURNAL, Vol.51(3) : 457-459, 2010 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2010
MeSH
Child, Preschool ; Diet, Ketogenic/adverse effects* ; Diet, Ketogenic/methods ; Epilepsy/diet therapy* ; Female ; Humans ; Kidney Calculi/etiology*
Keywords
Renal stone ; ketogenic diet ; epilepsy
Abstract
In this paper, we report on a 5-year-old girl who developed a renal stone while following the ketogenic diet to treat refractory seizure disorder. Three months after initiating the ketogenic diet, she developed severe abdominal pain and vomiting. The spot urine calcium-to-creatinine (Ca/Cr) ratio and 24-hour urine evaluation showed hypercalciuria. Computed tomography (CT) imaging revealed a stone in the right ureteropelvic junction, resulting in hydronephrosis of the right kidney. The renal stone disappeared 5 days after conservative treatment; the patient's microscopic hematuria resolved concurrently. In light of this case report, we recommend regularly monitoring the urine Ca/Cr ratio with ultrasonography for further development of renal stones in patients following the ketogenic diet. If these patients exhibit evidence of symptomatic hypercalciuria or cyristalluria, liberalization of fluid restriction and urine alkalization using oral potassium citrate should be considered.
Files in This Item:
T201003528.pdf Download
DOI
10.3349/ymj.2010.51.3.457
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Kim, Heung Dong(김흥동) ORCID logo https://orcid.org/0000-0002-8031-7336
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
Lee, Jae Seung(이재승)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/102342
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