The Effects of Hydroxyapatite Coated with β-Tricalcium Phosphate in One-Wall Intrabony Defects in Dogs

Abstract

The purpose of this study was to evaluate the effect of hydroxyapatite coated with β-tricalcium phosphate (HCT) in surgically prepared one-wall periodontal intrabony defects in dogs. Four beagle dogs were used as the subjects. One-wall intrabony defects were prepared surgically at the mandibular second and fourth premolars in both right and left jaw quadrants. The experimental groups were divided into two, according to the kind of graft material used. In the HCT group, the defect was filled with HCT. In the HCT/ACS group, the defect was filled with HCT and then covered by an absorbable collagen sponge (ACS). The control group was treated by root planing only. Histologic and histometric analyses revealed statistically significant bone formation in the HCT and HCT/ACS groups, compared with the control group. New bone was observed along the root surface or in close contact with the residual graft particles in the HCT and HCT/ACS groups. The HCT/ACS group showed statistically greater bone formation than the HCT group. It can be concluded that HCT provides osteoconductivity in one-wall intrabony defects. In addition, HCT in one-wall intrabony defects provide new cementum formation and periodontal ligament fiber formation with neither root resorption nor ankylosis.