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대장에 발생한 방사선속발 악성 섬유 조직구종

Other Titles
 Postradiation Malignant Fibrous Histiocytoma of the Colon: A Case Report 
Authors
 윤진영  ;  김도경  ;  천재희  ;  문창모  ;  박재준  ;  정주원  ;  김은영  ;  김태훈  ;  이찬주  ;  박은영  ;  신상훈  ;  홍성필  ;  김태일  ;  김남규  ;  김호근  ;  김원호 
Citation
 Intestinal Research, Vol.8(1) : 75-79, 2010 
Journal Title
 Intestinal Research 
ISSN
 1598-9100 
Issue Date
2010
Abstract
Post-radiation soft tissue sarcomas are recognized as rare complications of radiation therapy. The most common type of post-radiation soft tissue sarcoma is a malignant fibrous histiocytoma (MFH), which originates from mesenchymal cells with a predominance of histiocytes and fibroblasts. The two most common sites of occurrence for post-radiation soft tissue sarcomas are the chest wall and pelvic cavity. Post-radiation colorectal MFHs are extremely rare and all of the reported cases of post-radiation sarcomas have occurred >3 years after radiation therapy. Recently, we managed a case of colorectal MFH which developed in a 48-year-old male who had undergone a low anterior resection for rectal adenocarcinoma and had received chemoradiotherapy as adjuvant treatment. Twelve months after radiotherapy, a 4 cm mass was detected 8 cm superior to the anastomosis site on colonoscopic examination. A soft tissue sarcoma was suspected on pathologic examination of the biopsy specimen. Therefore, he underwent a Hartmann’s operation and the final pathologic finding revealed MFH with a storiform pattern of tumor cells composed of pleomorphic, multinucleated giant cells. This is the first case of MFH that had a latency period <3 years (i.e., 1 year) between the time of radiotherapy and diagnosis
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DOI
10.5217/ir.2010.8.1.75
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
김남규(Kim, Nam Kyu) ORCID logo https://orcid.org/0000-0003-0639-5632
김도영(Kim, Do Young)
김원호(Kim, Won Ho) ORCID logo https://orcid.org/0000-0002-5682-9972
김은영(Kim, Eun Young) ORCID logo https://orcid.org/0000-0002-3281-5744
김태일(Kim, Tae Il) ORCID logo https://orcid.org/0000-0003-4807-890X
김태훈(Kim, Tae Hoon)
김호근(Kim, Ho Keun)
문창모(Moon, Chang Mo)
박은영(Park, Eun Young)
박재준(Park, Jae Jun)
신상훈(Shin, Sang Hoon)
윤진영(Yoon, Jin Young)
이찬주(Lee, Chan Joo) ORCID logo https://orcid.org/0000-0002-8756-409X
정주원(Chung, Joo Won)
천재희(Cheon, Jae Hee) ORCID logo https://orcid.org/0000-0002-2282-8904
홍성필(Hong, Sung Pil)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101250
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