1 210

Cited 13 times in

Human orbitofrontal-striatum functional connectivity modulates behavioral persistence

Authors
 Young-Chul Jung  ;  Jeonghun Ku  ;  Kee Namkoong  ;  Wonho Lee  ;  Sun I. Kim  ;  Jae-Jin Kim 
Citation
 NEUROREPORT, Vol.21(7) : 502-506, 2010 
Journal Title
 NEUROREPORT 
ISSN
 0959-4965 
Issue Date
2010
MeSH
Adult ; Behavior/physiology* ; Brain/physiology* ; Brain Mapping* ; Decision Making/physiology* ; Female ; Humans ; Image Interpretation, Computer-Assisted ; Magnetic Resonance Imaging ; Male ; Neural Pathways/physiology* ; Young Adult
Keywords
functional connectivity ; orbitofrontal cortex ; persistence ; ventral striatum
Abstract
The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00001756-201005120-00005&LSLINK=80&D=ovft
DOI
10.1097/WNR.0b013e3283383482
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
Jung, Young Chul(정영철) ORCID logo https://orcid.org/0000-0002-0578-2510
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100897
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links