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CT-based abdominal aortic calcification score as a surrogate marker for predicting the presence of asymptomatic coronary artery disease

DC FieldValueLanguage
dc.contributor.author김명진-
dc.contributor.author안성수-
dc.contributor.author안찬식-
dc.contributor.author이혜선-
dc.contributor.author이혜정-
dc.contributor.author정용은-
dc.contributor.author최병욱-
dc.date.accessioned2015-01-06T17:37:00Z-
dc.date.available2015-01-06T17:37:00Z-
dc.date.issued2014-
dc.identifier.issn0938-7994-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/100312-
dc.description.abstractOBJECTIVES: To assess the value of a CT-based abdominal aortic calcification (AAC) score as a surrogate marker for the presence of asymptomatic coronary artery disease (CAD). METHODS: The AAC scores of 373 patients without cardiac symptoms who underwent both screening coronary CT angiography and abdominal CT within one year were calculated according to the Agatston method. Logistic regression was used to derive two multivariate models from traditional cardiovascular risk factors, with and without AAC scores, to predict the presence of CAD. The AAC score and the two multivariate models were compared by calculating the area under the receiver operating characteristic curve (AUC) and the net reclassification improvement (NRI). RESULTS: The AAC score alone showed a marginally higher AUC (0.823 vs. 0.767, P = 0.061) and significantly better risk classification (NRI = 0.158, P = 0.048) than the multivariate model without AAC. The multivariate model using traditional factors and AAC did not show a significantly higher AUC (0.832 vs. 0.823, P = 0.616) or NRI (0.073, P = 0.13) than the AAC score alone. The optimal cutoff value of the AAC score for predicting CAD was 1025.8 (sensitivity, 79.5 %; specificity, 75.9 %). CONCLUSIONS: AAC scores may serve as a surrogate marker for the presence or absence of asymptomatic CAD.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2491~2498-
dc.relation.isPartOfEUROPEAN RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAorta, Abdominal/diagnostic imaging*-
dc.subject.MESHAortic Diseases/complications-
dc.subject.MESHAortic Diseases/diagnostic imaging*-
dc.subject.MESHCoronary Angiography/methods*-
dc.subject.MESHCoronary Artery Disease/diagnostic imaging*-
dc.subject.MESHCoronary Artery Disease/etiology-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHImaging, Three-Dimensional-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHROC Curve-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, X-Ray Computed/methods*-
dc.subject.MESHVascular Calcification/complications-
dc.subject.MESHVascular Calcification/diagnostic imaging*-
dc.titleCT-based abdominal aortic calcification score as a surrogate marker for predicting the presence of asymptomatic coronary artery disease-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorChansik An-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorSung Soo Ahn-
dc.contributor.googleauthorByoung Wook Choi-
dc.contributor.googleauthorMyeong-Jin Kim-
dc.contributor.googleauthorYong Eun Chung-
dc.identifier.doi10.1007/s00330-014-3298-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03312-
dc.contributor.localIdA03320-
dc.contributor.localIdA02234-
dc.contributor.localIdA00426-
dc.contributor.localIdA02268-
dc.contributor.localIdA03662-
dc.contributor.localIdA04059-
dc.relation.journalcodeJ00851-
dc.identifier.eissn1432-1084-
dc.identifier.pmid25030461-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00330-014-3298-3-
dc.subject.keywordAbdominal aorta-
dc.subject.keywordVascular calcification-
dc.subject.keywordComputed tomography-
dc.subject.keywordCoronary angiography-
dc.subject.keywordAtherosclerosis-
dc.contributor.alternativeNameKim, Myeong Jin-
dc.contributor.alternativeNameAhn, Sung Soo-
dc.contributor.alternativeNameAn, Chan Sik-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameChung, Yong Eun-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorAhn, Sung Soo-
dc.contributor.affiliatedAuthorKim, Myeong Jin-
dc.contributor.affiliatedAuthorAn, Chan Sik-
dc.contributor.affiliatedAuthorChung, Yong Eun-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.rights.accessRightsfree-
dc.citation.volume24-
dc.citation.number10-
dc.citation.startPage2491-
dc.citation.endPage2498-
dc.identifier.bibliographicCitationEUROPEAN RADIOLOGY, Vol.24(10) : 2491-2498, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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