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Validation of Compliance Zone at Cerebral Arterial Bifurcation Using Phantom and Computational Fluid Dynamics Simulation

Authors
 Young-Jun Lee  ;  Yoon-Chul Rhim  ;  Moonho Choi  ;  Tae-Sub Chung 
Citation
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.38(3) : 480-484, 2014 
Journal Title
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 
ISSN
 0363-8715 
Issue Date
2014
MeSH
Angiography/instrumentation* ; Blood Flow Velocity ; Cerebral Arteries/anatomy & histology ; Cerebral Arteries/diagnostic imaging ; Cerebral Arteries/physiopathology* ; Cerebrovascular Circulation/physiology* ; Computer Simulation ; Equipment Design ; Humans ; Models, Cardiovascular* ; Models, Neurological ; Phantoms, Imaging* ; Pulsatile Flow/physiology* ; Vascular Resistance/physiology ; Vascular Stiffness/physiology
Keywords
aneurysm ; cerebral artery ; compliance ; phantom ; computational fluid dynamics
Abstract
OBJECTIVE: A zone compliant to pulsatile flow (compliance zone) showing evagination and flattening at the apex of the cerebral arterial bifurcation was documented in our previous report using electrocardiogram-gated computed tomographic and magnetic resonance angiography. We aimed to validate the existence of compliance zones and examine their relationship to local thin-elastic walls. METHODS: We examined different bifurcating vascular models: a phantom with a thin elastic region at the apex and computational fluid dynamics models with either an elastic or rigid region at the apex of a bifurcation. RESULTS: In the phantom, the elastic region at the apex of the bifurcation showed evagination and flattening in time with the pulsatile circulating fluids. The size of the evaginations increased when the outlet side was tilted down below the level of the flow-generating pump. Pulsatile evagination could be simulated in the computational fluid dynamics model with an elastic region at the bifurcation apex, and the pressure gradient was highest in the evaginating apex in peak systolic phase. CONCLUSIONS: We were able to demonstrate a compliance zone, which responds to pressure gradients, experimentally, in the form of a thin elastic region at an arterial bifurcation.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-201405000-00027&LSLINK=80&D=ovft
DOI
10.1097/RCT.0000000000000056
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Chung, Tae Sub(정태섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100011
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