Browsing by Yonsei Author : Park, Hye Jung

eperson profile image
Name :
Park, Hye Jung [박혜정]
orcid http://orcid.org/0000-0002-1862-1003
Department :
College of Medicine (의과대학) - Dept. of Internal Medicine (내과학교실)
Scopus ID :
Scopus (56734724500)

교수 기본정보

세부 전공
호흡기내과
이메일
Craft7820@yuhs.ac

실험실 기본정보

이름
천식연구소
위치
강남구 언주로 211 (도곡동 146-92) 강남세브란스병원 의생명연구센터
구분
Wet Lab (50%), Dry Lab (50%)

연구소개

연구 분야
연구 내용
1. 천식 환자들을 등록하여 임상 연구
- 천식 환자들 대상으로 하는 임상 연구 IRB 승인 및 연구 진행
- 1~4상의 다양한 임상 연구 진행
2. 천식 환자들의 데이터 이용한 후향적 관찰 연구
- 병원 내 천식 환자 데이터 이용한 후향적 연구 (SCRAP 이용)
- 빅데이터 (국민건강보험공단, 심평원, 국건영 자료 등 이용)
3. 천식 환자들의 검체 이용한 연구
- 천식 환자들의 혈액, 기관지폐포세척액, 폐조직 등을 얻어 다양한 정보를 획득 (유전자, proteomics 등) 하고 이를 이용하여 천식 아형의 분류, 예후 예측, 치료제 탐색 등의 연구 진행
4. 천식 마우스 모델 통한 연구
- 다양한 천식 마우스 모델 (OVA, HDM, 미세먼지, 비만 등) 이용
- 실험실 고유의 장비 (Flexivent 등) 및 강남세브란스병원 공용 장비 이용하여 다양한 천식 관련 지표 평가 (기도저항, 병리조직, ELISA, mRNA PCR, FACS, IF, IHC 등)
- 마우스 검체를 이용하여 genomics & proteomics 분석
- Single-cell RNA sequencing 진행
5. 세포 실험 연구
- 다양한 세포 모델 (OVA, HDM, insulin 등) 이용
- ELISA, mRNA PCR 등 분석

학생 참여 정보

학생들이 참여하면 좋을 연구
  • 본 연구실에서 하는 모든 연구에 관하여,
  • 학생이 관심있는 분야/범위/기간만큼 자유롭게 참여 가능
학생 참여 시 사용하게 되는 장비 및 프로그램
  • 참여 분야/범위/기간에 따라 다양함
참여 전 준비사항
  • 연구에 대한 의지
  • (※ 참여 분야/범위/기간에 따라 실험동물부 이용자 교육/IRB 교육 이수가 필요할 수 있음)

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Researcher Network

Showing results 1 to 50 of 119

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Issue DateTitleJournal Title
2026Clinicopathologic characteristics and genomic profiling of HER2-low advanced gastric or gastroesophageal junction cancer ESMO OPEN
2025Low levels of serum albumin and blood basophils as 10-year mortality predictors in a nationwide Korean COPD cohort SCIENTIFIC REPORTS
2025Impact of COVID-19 therapeutics on the development of post-infectious lung fibrosis FRONTIERS IN MICROBIOLOGY
2025Efficacy and safety of HL-301 compared with erdosteine in acute bronchitis: a randomized, double-blind, trial KOREAN JOURNAL OF INTERNAL MEDICINE
2025Dual Use of Electronic Cigarettes and Cigarettes Elevates Risk of Chronic Obstructive Pulmonary Disease and Mental Health Issues: Insights from a Korean Health Survey INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
2025Clinical characteristics and risk factors for escalation to anaphylaxis from non-severe drug hypersensitivity reaction CLINICAL AND TRANSLATIONAL ALLERGY
2025Features of Lung Cyst in Birt-Hogg-Dubé Syndrome from Patients with Multiple Lung Cysts TUBERCULOSIS AND RESPIRATORY DISEASES
2025Comparative Assessment of Acute Pulmonary Effects Induced by Heat-Not-Burn Tobacco Aerosol Inhalation in a Murine Model INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024Dynamic microbial changes in exacerbation of chronic obstructive pulmonary diseaseFRONTIERS IN MICROBIOLOGY
2024Appropriate Allergic Rhinitis Medications Can Reduce Systemic Steroid Requirement and Prevent RhinosinusitisJOURNAL OF CLINICAL MEDICINE
2024T-Cell Dynamics Predicts Prognosis of Patients with Hepatocellular Carcinoma Receiving Atezolizumab Plus BevacizumabINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024Anti-aminoacyl-tRNA synthetase-interacting multifunctional protein-1 antibody improves airway inflammation in mice with house dust mite induced asthmaWORLD ALLERGY ORGANIZATION JOURNAL
2024Angiotensin Receptor Blockers and the Risk of Suspected Drug-Induced Liver Injury: A Retrospective Cohort Study Using Electronic Health Record-Based Common Data Model in South KoreaDRUG SAFETY
2024Prescription patterns and effectiveness of medications for chronic obstructive pulmonary disease: A retrospective study of real-world settingsPLOS ONE
2024Development of a multiplex droplet digital PCR method for detection and monitoring of <i>Mycobacterium tuberculosis</i> and drug-resistant tuberculosisANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
2024Roles of Inflammatory Biomarkers in Exhaled Breath Condensates in Respiratory Clinical FieldsTUBERCULOSIS AND RESPIRATORY DISEASES
2023Effects of chitinase-1 inhibitor in obesity-induced and-aggravated asthma in a murine modelLIFE SCIENCES
2023Inhibition of Dickkopf-1 enhances the anti-tumor efficacy of sorafenib via inhibition of the PI3K/Akt and Wnt/β-catenin pathways in hepatocellular carcinomaCELL COMMUNICATION AND SIGNALING
2023Low Skeletal Muscle Mass and Clinical Outcomes in Chronic Obstructive Pulmonary DiseaseTuberculosis and Respiratory Diseases
2023Airflow obstruction and chronic obstructive pulmonary disease are common in pulmonary tuberculosis even without sequelae findings on chest X-rayINFECTIOUS DISEASES
2023Long-Term Clinical Outcomes of Patients with Chronic Obstructive Pulmonary Disease with SarcopeniaLIFE-BASEL
2023Asthma and increased risk of myocardial infarction and mortality among hypertensive Korean patientsHypertension Research
2023Outstanding Characteristics of Birt-Hogg-Dube Syndrome in KoreaDiagnostics
2023Association between Serum Levels of Interleukin-25/Thymic Stromal Lymphopoietin and the Risk of Exacerbation of Chronic Obstructive Pulmonary DiseaseBIOMOLECULES
2023Particulate matter10-induced airway inflammation and fibrosis can be regulated by chitinase-1 suppressionRESPIRATORY RESEARCH
2023Characteristic Chest Computed Tomography Findings for Birt-Hogg-Dube Syndrome Indicating Requirement for Genetic EvaluationDiagnostics
2022Multicenter Prospective Observational Study to Evaluate the Therapeutic Effect and Safety of a Combination of Montelukast and Levocetirizine for Allergic Rhinitis when Administered to Patients with Allergic Rhinitis and AsthmaInternational Archives of Allergy and Immunology
2022Differences in the Recurrence Rate of Immediate Adverse Drug Reactions According to the Components of Alternative Contrast Media: Analysis of Repetitive Computed Tomography Cases in a Single Tertiary HospitalDrug Safety
2022A Comparison of the Effectiveness of Asthma Medications on Asthma Exacerbations in Real World National CohortJournal of Asthma and Allergy
2022Management of hereditary angioedema in pediatric, pregnant, and breast-feeding patients: An expert opinionAllergy Asthma & Respiratory Diseases
2022Effects of Asthma Medication Type on Asthma Exacerbation in a Real-World SettingYonsei Medical Journal
2022Diagnosis and treatment of hereditary angioedema: An expert opinionAllergy Asthma & Respiratory Diseases
2022Qualitative focus group interview study of communication between patients, dentists and physicians for efficient osteonecrosis of the jaw practicesBMJ Open
2022Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary TuberculosisAntimicrobial Agents and Chemotherapy
2022사용 전 베타락탐 항생제 피부시험의 유용성에 대한 전문가 의견Allergy Asthma & Respiratory Diseases
2021E-cigarette-associated Severe Pneumonia in Korea Using Data Linkage between the Korea National Health and Nutrition Examination Survey (KNHANES, 2013-2019) and the National Health Insurance Service (NHIS) Claims DatabaseJournal of Korean Medical Science
2021Long-Term Prognosis of Asthma-Bronchiectasis Overlapped Patients: A Nationwide Population-Based Cohort StudyAllergy, Asthma & Immunology Research
2021Reliability of Portable Spirometry Performed in the Korea National Health and Nutrition Examination Survey Compared to Conventional SpirometryTuberculosis and Respiratory Diseases
2021Risk factors of beta-lactam anaphylaxis in Korea: A 6-year multicenter retrospective adult case-control studyWorld Allergy Organization Journal
2021Bone Radiomics Score Derived From DXA Hip Images Enhances Hip Fracture Prediction in Older WomenJOURNAL OF BONE AND MINERAL RESEARCH
2021Variable effects of underlying diseases on the prognosis of patients with COVID-19PLoS ONE
2021Low alanine aminotransferase as a risk factor for chronic obstructive pulmonary disease in malesScientific Reports
2021Intralymphatic immunotherapy with tyrosine-adsorbed allergens: a double-blind, placebo-controlled trialRESPIRATORY RESEARCH
2021Nicotine Dependence and Stress Susceptibility in E-Cigarette Smokers: The Korea National Health and Nutrition Examination Survey 2013-2017TUBERCULOSIS AND RESPIRATORY DISEASES
2021Obesity-induced Vitamin D Deficiency Contributes to Lung Fibrosis and Airway HyperresponsivenessAmerican Journal of Respiratory Cell and Molecular Biology
2021Influence of government-driven quality assessment program on patients with chronic obstructive pulmonary diseaseRESPIRATORY RESEARCH
2021Effect of asthma and asthma medication on the prognosis of patients with COVID-19EUROPEAN RESPIRATORY JOURNAL
2021Impact of the Asthma Quality Assessment Program on Burden of AsthmaJOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2021Effects of Particulate Matter 10 Inhalation on Lung Tissue RNA expression in a Murine Model TUBERCULOSIS AND RESPIRATORY DISEASES
2020Reactive oxygen species modulator 1 expression predicts lymph node metastasis and survival in early-stage non-small cell lung cancerPLoS ONE

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