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Development and validation of an electronic medical record-based disease activity index of Behcet's disease

 D. Kim  ;  M. Choi  ;  H. Kim  ;  S. Cho  ;  S. Cho  ;  D. Bang 
 Clinical and Experimental Rheumatology, Vol.32(84) : 40-44, 2014 
Journal Title
 Clinical and Experimental Rheumatology 
Issue Date
Adult ; Asian Continental Ancestry Group ; Behcet Syndrome/immunology* ; Behcet Syndrome/physiopathology* ; Blood Sedimentation ; C-Reactive Protein/metabolism ; Databases, Factual/standards* ; Databases, Factual/statistics & numerical data ; Electronic Health Records/organization & administration ; Electronic Health Records/standards* ; Electronic Health Records/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Observer Variation ; Prospective Studies ; Reproducibility of Results ; Severity of Illness Index*
OBJECTIVES: The disease activity of Behçet's disease is inadequately defined, and there is no consensus on how it should be measured. The aim of this study was to verify the usefulness of a simplified electronic medical record (EMR)-based activity index (EMRAI) for Behçet's disease. METHODS: A total of 73 Korean patients with Behçet's disease participated in this study. Two dermatologists interviewed each participant independently using two activity scoring systems: the EMRAI and the Behçet's Disease Current Activity Form (BDCAF). Overall agreement between raters, correlation between activity scoring indices, and total interview run-time were evaluated. RESULTS: The EMRAI significantly correlated with the BDCAF (Spearman's correlation coefficient, r=0.835), physician-assessed overall activity score (r=0.782), erythrocyte sedimentation rate (r=0.520) and C-reactive protein level (r=0.422). The weighted kappa score for inter-rater agreement of EMRAI showed very good reliability compared with that of BDCAF (0.894 and 0.693, respectively). The mean total run-time for the EMRAI was shorter than that required to administer the BDCAF (95 s and 115 s, respectively). CONCLUSIONS: The EMRAI, an EMR-based simplified activity index of Behçet's disease, facilitates rapid and simple gathering of disease activity data and clinical information.
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1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영) ORCID logo https://orcid.org/0000-0002-0194-9854
Kim, Ha Yan(김하얀)
Bang, Dong Sik(방동식)
Cho, Sung Bin(조성빈)
Cho, Su Hyun(조수현)
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