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Size discrepancy between endoscopic size and pathologic size is not negligible in endoscopic resection for early gastric cancer

DC FieldValueLanguage
dc.contributor.author강대용-
dc.contributor.author박준철-
dc.contributor.author송미경-
dc.contributor.author신성관-
dc.contributor.author심충남-
dc.contributor.author이상길-
dc.contributor.author이용찬-
dc.contributor.author이혁-
dc.contributor.author정현수-
dc.date.accessioned2015-01-06T17:05:57Z-
dc.date.available2015-01-06T17:05:57Z-
dc.date.issued2014-
dc.identifier.issn0930-2794-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/99344-
dc.description.abstractBACKGROUND: Accurate tumor size measurement is critical for selecting proper candidates for endoscopic resection (ER) of early gastric cancer (EGC). However, size discrepancy between endoscopic size and pathologic size often occurs during ER for EGC. OBJECTIVE: The purposes of this study were to investigate the clinicopathological characteristics related to size discrepancy and the clinical implications of size discrepancies in terms of therapeutic outcomes. METHODS: Between April 2006 and June 2013, a total of 820 patients with 826 EGCs underwent ER. Enrolled lesions were categorized into the following three groups based on size discrepancy between endoscopic size and pathologic size: well-estimated (N = 308), underestimated (N = 215), or overestimated (N = 303) lesions. The well-estimated group was defined as lesions with a ratio of endoscopic size to pathologic size from 0.7 to 1.3. RESULTS: The overall median size discrepancy was 5.0 mm (interquartile range 2.0-9.0). Size, location, macroscopic type, primary tumor stage, and histology differed significantly between the three groups. Larger size [odds ratio (OR) 5.07, 95 % confidence interval (CI) 3.38-7.59, p < 0.001], flat/depressed type (OR 1.71, 95% CI 1.15-2.55, p = 0.008), and undifferentiated histology (OR 2.24, 95% CI 1.31-3.83, p = 0.003) were independent risk factors for endoscopic size underestimation in multivariate analysis. Smaller size (OR 10.95, 95% CI 4.64-25.87, p < 0.001) was the only independent predictor for endoscopic overestimation of size. Significantly lower complete resection and curative resection rates were detected in the underestimated group compared with the well-estimated group, while the complete resection rate in the overestimated group tended to be higher than in the well-estimated group. There was no significant difference of curative resection rate between the overestimated and the well-estimated groups. CONCLUSIONS: Larger size, flat/depressed type, and undifferentiated histology of EGC carry a significant risk for endoscopic underestimation of lesion size, which results in the lower rates of complete and curative resections for EGC. Further studies to reduce size discrepancy are warranted.-
dc.description.statementOfResponsibilityopen-
dc.format.extent2199~2207-
dc.relation.isPartOfSURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenocarcinoma/pathology-
dc.subject.MESHAdenocarcinoma/surgery-
dc.subject.MESHAged-
dc.subject.MESHBiopsy-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHGastric Mucosa/pathology-
dc.subject.MESHGastroscopy*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHStomach Neoplasms/pathology*-
dc.subject.MESHStomach Neoplasms/surgery*-
dc.titleSize discrepancy between endoscopic size and pathologic size is not negligible in endoscopic resection for early gastric cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorChoong Nam Shim-
dc.contributor.googleauthorMi Kyung Song-
dc.contributor.googleauthorDae Ryong Kang-
dc.contributor.googleauthorHyun Soo Chung-
dc.contributor.googleauthorJun Chul Park-
dc.contributor.googleauthorHyuk Lee-
dc.contributor.googleauthorSung Kwan Shin-
dc.contributor.googleauthorSang Kil Lee-
dc.contributor.googleauthorYong Chan Lee-
dc.identifier.doi10.1007/s00464-014-3453-6-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01676-
dc.contributor.localIdA02020-
dc.contributor.localIdA02112-
dc.contributor.localIdA02214-
dc.contributor.localIdA02812-
dc.contributor.localIdA02988-
dc.contributor.localIdA03285-
dc.contributor.localIdA00009-
dc.relation.journalcodeJ02703-
dc.identifier.eissn1432-2218-
dc.identifier.pmid24519032-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00464-014-3453-6-
dc.subject.keywordEarly gastric cancer-
dc.subject.keywordSize-
dc.subject.keywordDiscrepancy-
dc.subject.keywordEndoscopic resection-
dc.contributor.alternativeNameKang, Dae Ryong-
dc.contributor.alternativeNamePark, Jun Chul-
dc.contributor.alternativeNameSong, Mi Kyung-
dc.contributor.alternativeNameShin, Sung Kwan-
dc.contributor.alternativeNameShim, Choong Nam-
dc.contributor.alternativeNameLee, Sang Kil-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.alternativeNameLee, Hyuk-
dc.contributor.alternativeNameChung, Hyun Soo-
dc.contributor.affiliatedAuthorPark, Jun Chul-
dc.contributor.affiliatedAuthorSong, Mi Kyung-
dc.contributor.affiliatedAuthorShin, Sung Kwan-
dc.contributor.affiliatedAuthorShim, Choong Nam-
dc.contributor.affiliatedAuthorLee, Sang Kil-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.contributor.affiliatedAuthorLee, Hyuk-
dc.contributor.affiliatedAuthorKang, Dae Ryong-
dc.rights.accessRightsfree-
dc.citation.volume28-
dc.citation.number7-
dc.citation.startPage2199-
dc.citation.endPage2207-
dc.identifier.bibliographicCitationSURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol.28(7) : 2199-2207, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers

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