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Effect of a new combined therapy with nano-carbonate apatite and CO2 laser on dentin hypersensitivity in an in situ model

Authors
 Han Sun Young  ;  Kim Ji Sun  ;  Kim Young Seok  ;  Kwon Ho Keun  ;  Kim Baek Il 
Citation
 PHOTOMEDICINE AND LASER SURGERY, Vol.32(7) : 394-400, 2014 
Journal Title
PHOTOMEDICINE AND LASER SURGERY
ISSN
 1549-5418 
Issue Date
2014
MeSH
Apatites/administration & dosage* ; Cross-Over Studies ; Dentifrices/therapeutic use* ; Dentin Sensitivity/drug therapy* ; Humans ; Lasers, Gas* ; Random Allocation ; Single-Blind Method
Abstract
OBJECTIVE:
The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model.
BACKGROUND DATA:
The synergic effect of this combination was demonstrated in an in vitro study.
METHODS:
This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20% n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope.
RESULTS:
The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20% higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups.
CONCLUSIONS:
The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.
Full Text
http://online.liebertpub.com/doi/abs/10.1089/pho.2014.3710
DOI
10.1089/pho.2014.3710
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Preventive Dentistry and Public Oral Health (예방치과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ho Keun(권호근)
Kim, Baek Il(김백일) ORCID logo https://orcid.org/0000-0001-8234-2327
Kim, Young Seok(김영석)
Kim, Ji Sun(김지선)
Han, Sun Young(한선영)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/99062
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