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Cited 3 times in

Short stature and ischemic stroke in nonvalvular atrial fibrillation: New insight into the old observation.

DC FieldValueLanguage
dc.contributor.author이혜정-
dc.contributor.author정보영-
dc.contributor.author하종원-
dc.contributor.author김영진-
dc.contributor.author김종윤-
dc.contributor.author박희남-
dc.contributor.author이문형-
dc.date.accessioned2015-01-06T16:52:48Z-
dc.date.available2015-01-06T16:52:48Z-
dc.date.issued2014-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98946-
dc.description.abstractBACKGROUND: For decades, repeated epidemiologic observations have been made regarding the inverse relationship between stature and cardiovascular disease, including stroke. However, the concept has not been fully evaluated in patients with atrial fibrillation (AF). We investigated whether patient's height is associated with ischemic stroke in patients with nonvalvular AF and attempted to ascertain a potential mechanism. METHODS: All 558 AF patients were enrolled: 211 patients with ischemic stroke (144 men, 68 ± 10 years) and 347 no-stroke patients (275 men, 56 ± 11 years) as a control group. Clinical characteristics and echocardiographic parameters were compared between the two groups. RESULTS: (1) Stroke patients were shorter than those in the control group (164 ± 8, vs. 169 ± 8 cm, p<0.001). However, body mass index failed to predict ischemic stroke; (2) Short stature (OR 0.93, 95% CI 0.91-0.95, p<0.001) along with left atrial (LA) anterior-posterior diameter and diastolic mitral inflow velocity (E) to diastolic mitral annuls velocity (E') (E/E') were independent predictor of stroke; (3) Height showed inverse correlation with E/E' independently, even after adjusting for other variables, including age, sex, and body weight, and comorbidities β -0.20, p=0.003); (4) LA size showed no correlation with stature (R=-0.06, p=0.18), whereas left ventricular size increases according to height of patients. CONCLUSIONS: Short stature is associated with occurrence of ischemic stroke and diastolic dysfunction in patients with AF and preserved systolic function. Height is a non-modifiable risk factor of stroke and might be more important than obesity in Asian AF patients, who are relatively thinner than western populations.-
dc.description.statementOfResponsibilityopen-
dc.format.extent541~544-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAtrial Fibrillation/diagnosis-
dc.subject.MESHAtrial Fibrillation/epidemiology*-
dc.subject.MESHAtrial Fibrillation/physiopathology-
dc.subject.MESHBody Height/physiology*-
dc.subject.MESHBrain Ischemia/diagnosis-
dc.subject.MESHBrain Ischemia/epidemiology*-
dc.subject.MESHBrain Ischemia/physiopathology-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHStroke/diagnosis-
dc.subject.MESHStroke/epidemiology*-
dc.subject.MESHStroke/physiopathology-
dc.titleShort stature and ischemic stroke in nonvalvular atrial fibrillation: New insight into the old observation.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJeonggeun Moon-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorJong-Youn Kim-
dc.contributor.googleauthorHui-Nam Pak-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorBoyoung Joung-
dc.identifier.doi10.1016/j.ijcard.2014.04.154-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03609-
dc.contributor.localIdA04257-
dc.contributor.localIdA00926-
dc.contributor.localIdA01776-
dc.contributor.localIdA02766-
dc.contributor.localIdA00727-
dc.contributor.localIdA03320-
dc.relation.journalcodeJ01093-
dc.identifier.eissn1874-1754-
dc.identifier.pmid24814538-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0167527314008341-
dc.subject.keywordAtrial fibrillation-
dc.subject.keywordDiastolic function-
dc.subject.keywordEchocardiography-
dc.subject.keywordHeight-
dc.subject.keywordStroke-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.alternativeNamePak, Hui Nam-
dc.contributor.alternativeNameLee, Moon Hyoung-
dc.contributor.affiliatedAuthorJoung, Bo Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorKim, Jong Youn-
dc.contributor.affiliatedAuthorPak, Hui Nam-
dc.contributor.affiliatedAuthorLee, Moon Hyoung-
dc.contributor.affiliatedAuthorKim, Young Jin-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.rights.accessRightsfree-
dc.citation.volume174-
dc.citation.number3-
dc.citation.startPage541-
dc.citation.endPage544-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.174(3) : 541-544, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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