Cited 21 times in
Multimeric grain-marked micelles for highly efficient photodynamic therapy and magnetic resonance imaging of tumors
DC Field | Value | Language |
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dc.contributor.author | 오영택 | - |
dc.date.accessioned | 2015-01-06T16:50:42Z | - |
dc.date.available | 2015-01-06T16:50:42Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0378-5173 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98879 | - |
dc.description.abstract | Multimeric grain-marked micelles consisting of an inner core micelle (for Fe3O4 encapsulation) and outer multi-grain micelles (for chlorin e6 (Ce6, a model drug) encapsulation) were fabricated using a micelle-to-micelle conjugation method. Grain micelles (mono-thiol functionalized micelles) were chemically linked to the surface of the core micelle (multi-maleimide functionalized micelle). These micelles enable discrete compartments for Ce6 and iron oxide (Fe3O4) that enable a significantly increased in vivo photodynamic tumor inhibition while preserving high contrast magnetic resonance (MR) imaging of the tumor in vivo. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 166~172 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF PHARMACEUTICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cell Line, Tumor | - |
dc.subject.MESH | Drug Carriers/chemistry* | - |
dc.subject.MESH | Drug Liberation | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Magnetite Nanoparticles/chemistry* | - |
dc.subject.MESH | Mice, Nude | - |
dc.subject.MESH | Micelles | - |
dc.subject.MESH | Neoplasms*/drug therapy | - |
dc.subject.MESH | Neoplasms*/pathology | - |
dc.subject.MESH | Photochemotherapy/methods* | - |
dc.subject.MESH | Porphyrins/administration & dosage* | - |
dc.subject.MESH | Porphyrins/chemistry | - |
dc.subject.MESH | Radiation-Sensitizing Agents/administration & dosage* | - |
dc.subject.MESH | Radiation-Sensitizing Agents/chemistry | - |
dc.subject.MESH | Surface Properties | - |
dc.subject.MESH | Xenograft Model Antitumor Assays | - |
dc.title | Multimeric grain-marked micelles for highly efficient photodynamic therapy and magnetic resonance imaging of tumors | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Ung Yeol Lee | - |
dc.contributor.googleauthor | Young Taik Oh | - |
dc.contributor.googleauthor | Dongin Kim | - |
dc.contributor.googleauthor | Eun Seong Lee | - |
dc.identifier.doi | 10.1016/j.ijpharm.2014.05.028 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02390 | - |
dc.relation.journalcode | J01150 | - |
dc.identifier.eissn | 1873-3476 | - |
dc.identifier.pmid | 24858385 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0378517314003688 | - |
dc.subject.keyword | Chlorin e6 (Ce6) | - |
dc.subject.keyword | Grain-marked micelles | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Multimeric micelles | - |
dc.subject.keyword | Photodynamic therapy | - |
dc.contributor.alternativeName | Oh, Young Taik | - |
dc.contributor.affiliatedAuthor | Oh, Young Taik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 471 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 166 | - |
dc.citation.endPage | 172 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol.471(1-2) : 166-172, 2014 | - |
dc.identifier.rimsid | 38841 | - |
dc.type.rims | ART | - |
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