YUHSpace

BROWSE

Export
1 472

Cited 10 times in

Surface charge switching nanoparticles for magnetic resonance imaging

DC Field Value Language
dc.contributor.author오영택-
dc.date.accessioned2015-01-06T16:49:38Z-
dc.date.available2015-01-06T16:49:38Z-
dc.date.issued2014-
dc.identifier.issn0378-5173-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98845-
dc.description.abstractIn this study, polypeptide-based nanoparticles [constituted using poly(l-lysine) coupled with deoxycholic acid (DOCA) and conjugated with 2,3-dimethylmaleic acid (DMA)] have high tumor selectivity once electrostatically switched by the acidic milieu of solid tumors. These nanoparticles exhibited a significantly increased in vitro cellular uptake and high accumulation in the acidic tumor site in vivo. Consequently, Fe3O4-loaded nanoparticles enabled high contrast magnetic resonance (MR) imaging of the tumor in vivo.-
dc.description.statementOfResponsibilityopen-
dc.format.extent127~134-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF PHARMACEUTICS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHContrast Media/chemistry*-
dc.subject.MESHDeoxycholic Acid/analogs & derivatives*-
dc.subject.MESHDeoxycholic Acid/chemistry-
dc.subject.MESHFemale-
dc.subject.MESHFlow Cytometry-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging*-
dc.subject.MESHMagnetite Nanoparticles/chemistry*-
dc.subject.MESHMice, Nude-
dc.subject.MESHMicroscopy, Confocal-
dc.subject.MESHMicroscopy, Fluorescence-
dc.subject.MESHNeoplasms, Experimental/metabolism-
dc.subject.MESHNeoplasms, Experimental/pathology-
dc.subject.MESHParticle Size-
dc.subject.MESHPolylysine/chemistry*-
dc.subject.MESHStatic Electricity-
dc.subject.MESHSurface Properties-
dc.titleSurface charge switching nanoparticles for magnetic resonance imaging-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorDong Jin Lee-
dc.contributor.googleauthorYoung Taik Oh-
dc.contributor.googleauthorEun Seong Lee-
dc.identifier.doi10.1016/j.ijpharm.2014.05.029-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02390-
dc.relation.journalcodeJ01150-
dc.identifier.eissn1873-3476-
dc.identifier.pmid24858382-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S037851731400369X-
dc.subject.keywordFe(3)O(4)-
dc.subject.keywordMagnetic resonance imaging (MRI)-
dc.subject.keywordSurface charge switching nanoparticle-
dc.subject.keywordpH-Responsive-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.rights.accessRightsfree-
dc.citation.volume471-
dc.citation.number1-2-
dc.citation.startPage127-
dc.citation.endPage134-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF PHARMACEUTICS, Vol.471(1-2) : 127-134, 2014-
dc.identifier.rimsid38822-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Show simple item record Find it @ YMLIB

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

  • License
    sherpa_romeo
    sherpa_juliet

OAK

DSpace Software Copyright © 2002-2017 Duraspace Yonsei University Medical Library All right Reserves. / TEL:02-2228-2915 /
YUHSpace는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.

Browse

Links