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Choroidal Thickness, Age, and Refractive Error in Healthy Korean Subjects

Authors
 Min Kim  ;  Sung Soo Kim  ;  Hyoung Jun Koh  ;  Sung Chul Lee 
Citation
 OPTOMETRY AND VISION SCIENCE, Vol.91(5) : 491-496, 2014 
Journal Title
 OPTOMETRY AND VISION SCIENCE 
ISSN
 1040-5488 
Issue Date
2014
MeSH
Adolescent ; Adult ; Aged ; Aging/physiology* ; Asian Continental Ancestry Group ; Axial Length, Eye/anatomy & histology ; Choroid/anatomy & histology* ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Organ Size ; Refractive Errors/epidemiology* ; Republic of Korea/epidemiology ; Tomography, Optical Coherence/methods ; Young Adult
Keywords
choroidal thickness ; EDI-OCT ; choroid ; choroidal imaging ; OCT
Abstract
PURPOSE: To investigate choroidal thickness (CT) in healthy Korean subjects measured by enhanced depth imaging optical coherence tomography and its association with age, axial length, and refractive error. METHODS: Choroidal scans using enhanced depth imaging optical coherence tomography in each eye of 286 healthy eyes were obtained at the macula. Choroidal thickness was measured at the fovea. Two separate line scans were obtained (one horizontal and one vertical). RESULTS: The mean (±SD) age was 40.18 (±17.89) years (range, 13 to 75 years). The mean (±SD) subfoveal CT was 307.26 (±95.18) μm. Multivariable linear regression suggested that age and refractive error were the most significant factors associated with subfoveal CT (all p < 0.0001) with an adjusted R = 0.181. In subjects younger than 60 years, refractive error or axial length and age retained statistically significant correlation with subfoveal CT, whereas such a relationship was lost in subjects older than 60 years. CONCLUSIONS: The mean subfoveal CT measurement showed the most significant positive correlation with refractive error and the most significant negative correlation with age. For patients younger than 60 years, there was a significant correlation of subfoveal CT with age and refractive error or axial length, whereas such significant association was not observed in subjects older than 60 years.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00006324-201405000-00005&LSLINK=80&D=ovft
DOI
10.1097/OPX.0000000000000229
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kim, Min(김민) ORCID logo https://orcid.org/0000-0003-1873-6959
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98835
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