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Prevalence and extent of atherosclerotic coronary artery disease and related outcome based on coronary computed tomographic angiography in asymptomatic elderly patients: retrospective cohort study

DC FieldValueLanguage
dc.contributor.author김영진-
dc.contributor.author김태훈-
dc.contributor.author김희영-
dc.contributor.author이지원-
dc.contributor.author이혜정-
dc.contributor.author장혁재-
dc.contributor.author최병욱-
dc.contributor.author허진-
dc.contributor.author홍유진-
dc.date.accessioned2015-01-06T16:42:10Z-
dc.date.available2015-01-06T16:42:10Z-
dc.date.issued2014-
dc.identifier.issn1569-5794-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98601-
dc.description.abstractThere is little data regarding coronary artery disease (CAD) and/or atherosclerotic plaques on coronary computed tomographic angiography (CCTA) among the elderly and its outcome, especially in asymptomatic patients. Using CCTA, we evaluated the prevalence and extent of CAD and/or atherosclerosis and related outcomes in asymptomatic elderly patients as compared with symptomatic elderly patients. The study included 1,196 consecutive patients aged 70 years or older who underwent CCTA over a 2-year period. Data were retrospectively evaluated for clinical cardiovascular risk factors with co-morbidities, and CCTA findings, including calcium scores, atherosclerotic plaques (number, plaque-segment score, plaque-extent score, and plaque-significant score) and presence of significant CAD. Follow-up data for active management and all-cause mortality after CCTA were collected for 2 years. Two-sided Student’s t test for independent samples, Chi square contingency tables, and Kaplan–Meier survival curves were used for statistical analysis. Data for 454 asymptomatic and 742 symptomatic elderly patients were analyzed. The prevalence of significant CAD and the extent of atherosclerotic plaques did not differ between the two groups (all P > 0.05). Asymptomatic patients with significant CAD on CCTA, were less likely to receive active management (P < 0.001), which may be related to the higher death rate in this group (P = 0.012) than in the symptomatic patients with significant CAD. Overall, symptoms were not related to the presence of significant CAD or to the extent of atherosclerosis in these elderly patients. However, all-cause mortality was higher in the asymptomatic patients with significant CAD than in the symptomatic ones-
dc.description.statementOfResponsibilityopen-
dc.format.extent669~676-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHCohort Studies-
dc.subject.MESHComorbidity-
dc.subject.MESHCoronary Angiography/methods*-
dc.subject.MESHCoronary Artery Disease/diagnostic imaging*-
dc.subject.MESHCoronary Artery Disease/epidemiology*-
dc.subject.MESHCoronary Artery Disease/therapy-
dc.subject.MESHCoronary Stenosis/diagnostic imaging-
dc.subject.MESHCoronary Stenosis/epidemiology-
dc.subject.MESHCoronary Stenosis/therapy-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGeriatric Assessment/methods-
dc.subject.MESHGeriatric Assessment/statistics & numerical data-
dc.subject.MESHHumans-
dc.subject.MESHImage Processing, Computer-Assisted/methods-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHPatient Outcome Assessment*-
dc.subject.MESHPlaque, Atherosclerotic/diagnostic imaging-
dc.subject.MESHPlaque, Atherosclerotic/epidemiology-
dc.subject.MESHPlaque, Atherosclerotic/therapy-
dc.subject.MESHPrevalence-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHTomography, X-Ray Computed/methods*-
dc.titlePrevalence and extent of atherosclerotic coronary artery disease and related outcome based on coronary computed tomographic angiography in asymptomatic elderly patients: retrospective cohort study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorHye-Jeong Lee-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorJin Hur-
dc.contributor.googleauthorJi Won Lee-
dc.contributor.googleauthorYoo Jin Hong-
dc.contributor.googleauthorHee Yeong Kim-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorTae Hoon Kim-
dc.contributor.googleauthorByoung Wook Choi-
dc.identifier.doi10.1007/s10554-014-0366-3-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01213-
dc.contributor.localIdA03490-
dc.contributor.localIdA04059-
dc.contributor.localIdA04370-
dc.contributor.localIdA04422-
dc.contributor.localIdA00727-
dc.contributor.localIdA03320-
dc.contributor.localIdA01086-
dc.contributor.localIdA03204-
dc.relation.journalcodeJ01094-
dc.identifier.eissn1875-8312-
dc.identifier.pmid24452728-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10554-014-0366-3-
dc.subject.keywordElderly patient-
dc.subject.keywordOld patient-
dc.subject.keywordCoronary artery disease-
dc.subject.keywordCoronary CT angiography-
dc.subject.keywordOutcome-
dc.contributor.alternativeNameKim, Young Jin-
dc.contributor.alternativeNameKim, Tae Hoon-
dc.contributor.alternativeNameKim, Hee Yeong-
dc.contributor.alternativeNameLee, Ji Won-
dc.contributor.alternativeNameLee, Hye Jeong-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameHur, Jin-
dc.contributor.alternativeNameHong, Yoo Jin-
dc.contributor.affiliatedAuthorKim, Hee Yeong-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorHur, Jin-
dc.contributor.affiliatedAuthorHong, Yoo Jin-
dc.contributor.affiliatedAuthorKim, Young Jin-
dc.contributor.affiliatedAuthorLee, Hye Jeong-
dc.contributor.affiliatedAuthorKim, Tae Hoon-
dc.contributor.affiliatedAuthorLee, Ji Won-
dc.rights.accessRightsfree-
dc.citation.volume30-
dc.citation.number3-
dc.citation.startPage669-
dc.citation.endPage676-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.30(3) : 669-676, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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