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Thyroid Nodules with Macrocalcification:Sonographic Findings Predictive of Malignancy

DC Field Value Language
dc.contributor.author곽진영-
dc.contributor.author김은경-
dc.contributor.author김정아-
dc.contributor.author박연주-
dc.contributor.author박정수-
dc.contributor.author손은주-
dc.contributor.author육지현-
dc.date.accessioned2015-01-06T16:28:17Z-
dc.date.available2015-01-06T16:28:17Z-
dc.date.issued2014-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98166-
dc.description.abstractPURPOSE: To analyze which sonographic features of thyroid nodules with macrocalcifications were predictable of thyroid malignancy. MATERIALS AND METHODS: We reviewed sonographic findings of 854 macrocalcified thyroid nodules in patients who underwent fine needle aspiration biopsy between December 2009 and January 2011. There were 171 non-diagnostic aspirations, 34 nodules with category 3, 4, 5 based on Bethesda system, which were not confirmed by surgery, and these nodules were excluded from the analysis. Sonographic characteristics of the macrocalcifications including its thickness, interruption, and existence of soft tissue rim outside the macrocalcification were analyzed. Other sonographic characteristics of nodules such as shape, margin, composition, echo pattern, vascularity, and underlying parenchymal echogenicity were also evaluated. The correlation of sonographic features with cytopathologic results and the diagnostic performance of sonographic features for the prediction of malignancy were analyzed. RESULTS: Among 649 nodules, 179 (27.6%) nodules were malignant and 470 (72.4%) nodules were benign. Among the features of the macrocalcification, interruption, irregular thickness, or the presence of soft tissue outside calcification rim were associated with malignancy (p<0.001). A high sensitivity and negative predictive values for the prediction of malignancy was found in sonographic characteristics of irregular thickness (92.2% and 91.0%, respectively) and the presence of soft tissue (88.5% and 88.8%, respectively). CONCLUSION: Sonographic characteristics of macrocalcification such as interruption, irregular thickness and the presence of soft tissue rim were associated with malignancy in thyroid nodules with macrocalcifications.-
dc.description.statementOfResponsibilityopen-
dc.format.extent339~344-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBiopsy, Fine-Needle-
dc.subject.MESHCalcinosis/diagnostic imaging*-
dc.subject.MESHCalcinosis/pathology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHThyroid Neoplasms/diagnostic imaging*-
dc.subject.MESHThyroid Neoplasms/pathology*-
dc.subject.MESHThyroid Nodule/diagnostic imaging*-
dc.subject.MESHThyroid Nodule/pathology*-
dc.subject.MESHUltrasonography-
dc.titleThyroid Nodules with Macrocalcification:Sonographic Findings Predictive of Malignancy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorYun Joo Park-
dc.contributor.googleauthorJeong-Ah Kim-
dc.contributor.googleauthorEun Ju Son-
dc.contributor.googleauthorJi Hyun Youk-
dc.contributor.googleauthorEun-Kyung Kim-
dc.contributor.googleauthorJin Young Kwak-
dc.contributor.googleauthorCheong Soo Park-
dc.identifier.doi10.3349/ymj.2014.55.2.339-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01646-
dc.contributor.localIdA00182-
dc.contributor.localIdA00801-
dc.contributor.localIdA00888-
dc.contributor.localIdA01561-
dc.contributor.localIdA01988-
dc.contributor.localIdA02537-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid24532501-
dc.identifier.urlhttp://www.eymj.org/DOIx.php?id=10.3349/ymj.2014.55.2.339-
dc.subject.keywordSonography-
dc.subject.keywordmacrocalcification-
dc.subject.keywordpapillary thyroid cancer-
dc.contributor.alternativeNameKwak, Jin Young-
dc.contributor.alternativeNameKim, Eun Kyung-
dc.contributor.alternativeNameKim, Jeong Ah-
dc.contributor.alternativeNamePark, Yun Joo-
dc.contributor.alternativeNamePark, Cheong Soo-
dc.contributor.alternativeNameSon, Eun Ju-
dc.contributor.alternativeNameYouk, Ji Hyun-
dc.contributor.affiliatedAuthorPark, Cheong Soo-
dc.contributor.affiliatedAuthorKwak, Jin Young-
dc.contributor.affiliatedAuthorKim, Eun-Kyung-
dc.contributor.affiliatedAuthorKim, Jeong Ah-
dc.contributor.affiliatedAuthorPark, Yun Joo-
dc.contributor.affiliatedAuthorSon, Eun Ju-
dc.contributor.affiliatedAuthorYouk, Ji Hyun-
dc.rights.accessRightsfree-
dc.citation.volume55-
dc.citation.number2-
dc.citation.startPage339-
dc.citation.endPage344-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.55(2) : 339-344, 2014-
dc.identifier.rimsid50692-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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