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간내 원발 병소가 뚜렷하지 않고 폐전이로 확진된 간세포암종 1예

Other Titles
 A case of lung metastasis from unknown primary hepatocellular carcinoma 
 문희선  ;  백용한  ;  권지은  ;  이관식  ;  문종태  ;  황성준  ;  장진혁 
 Korean Journal of Medicine, Vol.72(suppl. 2) : 149-155, 2007 
Journal Title
Korean Journal of Medicine
Issue Date
Hepatocellular carcinoma (HCC) is a common malignancy and hepatitis B infection is known to be its most common etiologic factor. The most common metastatic site of extrahepatic spread is the lung. We report here on a case of a patient who presented with pulmonary metastasis as the first clinical manifestation of HCC. A 62-year-old-male patient showed an elevated α-fetoprotein level during follow up for chronic hepatitis B and liver cirrhosis. The existence of HCC was suspected and an empirical imaging diagnosis was performed. However, repeated computer tomography (CT), magnetic resonance imaging and hepatic angiography failed to detect any HCC. After 12 months, chest CT and PET (positron emission tomography) revealed lung nodules. Histologically, the resected lesion was confirmed as metastatic tumor from HCC. The establishment of the diagnosis of metastatic HCC can occasionally be problematic, particularly when the primary tumor has not been identified. A systemic approach to diagnosis and treatment should be followed
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ji Eun(권지은)
Moon, Jong Tae(문종태)
Paik, Yong Han(백용한)
Lee, Kwan Sik(이관식) ORCID logo https://orcid.org/0000-0002-3672-1198
Hwhang, Sung Jun(황성준)
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