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정신분열병 환자의 복부지방 및 대퇴중간 저밀도 근육 면적 평가

Other Titles
 Assessment of Abdominal Fat and Mid-Thigh Low-Density Muscle Areas in Patients with Schizophrenia 
 김철식  ;  남윤영  ;  김찬형  ;  차경렬  ;  김경래  ;  안철우  ;  남지선  ;  노태웅  ;  김혜진  ;  박종숙 
 Korean Journal of Psychopharmacology (대한정신약물학회지), Vol.18(2) : 81-85, 2007 
Journal Title
 Korean Journal of Psychopharmacology (대한정신약물학회지) 
Issue Date
Objective : Patients with schizophrenia are at a higher risk for developing insulin resistance and type 2 diabetes mellitus (T2DM). However, few studies have examined abdominal fat and mid-thigh low-density muscle areas, which are known risk factors for insulin resistance and T2DM, in patients with schizophrenia. Therefore, we measured the abdominal fat and mid-thigh low-density muscle areas of schizophrenics and compared them with normal controls. Methods:Nineteen (four men and 15 women) drug-naive or -free subjects who met the DSM IV criteria for schizophrenia and 19 age- and sex-matched controls were recruited. We measured weight, height, waist circumference, and percent body fat, and calculated the body mass index (BMI). Abdominal fat and mid-thigh low-density muscle areas were evaluated using computed tomography. Results:There was no significant difference in terms of age and BMI between the two groups. The areas of abdominal fat (262.4±101.8 vs. 257.1±93.8 ㎠;p=0.919), subcutaneous fat (182.4±72.8 vs. 180.5±75.1 ㎠;p=0.988), visceral fat (79.9±47.2 vs. 76.6±49.3 ㎠; p=0.872), and mid-thigh low-density muscle (15.0±9.9 vs. 15.4±5.2 ㎠, p=0.373) did not differ between schizophrenics and controls. Conclusion:Abdominal obesity is a well-recognized risk factor for developing certain medical conditions such as insulin resistance and T2DM. We demonstrated that drug-naive or- free patients with schizophrenia do not have increased visceral fat or mid-thigh low-density muscle areas, which might have explained the higher prevalence of insulin resistance and T2DM in these patients.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Rae(김경래)
Kim, Chan Hyung(김찬형)
Kim, Chul Sik(김철식)
Kim, Hae Jin(김혜진)
Nam, Yoon Young(남윤영)
Nam, Ji Sun(남지선) ORCID logo https://orcid.org/0000-0001-8655-5258
Noh, Tae Woong(노태웅)
Park, Jong Suk(박종숙) ORCID logo https://orcid.org/0000-0002-5385-1373
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Cha, Kyung Ryeol(차경렬)
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