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Effects Of (1→3), (1→6)-β-D-Glucan Behavior in Human Dermal Fibroblast Cells under Serum Starvation

Authors
 Yeon I Woo  ;  Hyun Joo Son  ;  Jong Chul Park  ;  Kazufumi Tsubaki  ;  Hyun Sook Baek  ;  Mi Hee Lee  ;  Hye Ryeon Lim 
Citation
 Key Engineering Materials, Vol.342-343 : 401-404, 2007 
Journal Title
 Key Engineering Materials 
ISSN
 1013-9826 
Issue Date
2007
Abstract
Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.
Full Text
http://www.scientific.net/KEM.342-343.401
DOI
10.4028/www.scientific.net/KEM.342-343.401
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
Park, Jong Chul(박종철) ORCID logo https://orcid.org/0000-0003-0083-5991
Baek, Hyun Sook(백현숙)
Son, Hyun Joo(손현주)
Woo, Yeon I.(우연이)
Lee, Mi Hee(이미희) ORCID logo https://orcid.org/0000-0002-9630-7044
Lim, Hye Ryeon(임혜련)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96780
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